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Table 1 Characteristics of the patients

From: Association between plasma ADAMTS-7 levels and ventricular remodeling in patients with acute myocardial infarction

Characteristics

LVEF ≤35% ( n= 42)

LVEF >35% ( n= 112)

Controls ( n= 38)

P value b

Age, years

66.5 ± 12.4

68.7 ± 10.4

56.6 ± 11.5

<0.05

Gender, male/female

28/14 (66.7/33.3%)

71/41 (63.4/36.6%)

21/17 (55.6%/44.7%)

<0.05

BMI (kg/m2)

24.4 ± 3.0

24.7 ± 3.8

26.1 ± 4.1

0.23

History of smoking, n (%)

12 (28.6)

30 (26.5)

11 (28.9)

0.42

Serum creatinine >140 μmol/L, n (%)

13 (30.95)a

6 (5.36)a

0 (0.00)

<0.05

History of hypertension, n (%)

28 (66.7)

73 (65.2)

16 (42.1)

<0.05

History of diabetes, n (%)

19 (45.2)

54 (48.2)

9 (23.7)

<0.05

Glucose (mmol/L)

8.17 ± 3.86

8.42 ± 3.56

5.64 ± 1.21

0.23

Total cholesterol (mmol/L)

4.64 ± 0.85

4.36 ± 1.17

4.66 ± 0.89

0.90

Triglycerides (mmol/L)

1.59 ± 1.21

1.38 ± 0.72

1.88 ± 1.34

0.08

HDL-cholesterol (mmol/L)

1.07 ± 0.33

1.12 ± 0.29

1.06 ± 0.32

0.06

LDL-cholesterol (mmol/L)

2.83 ± 0.84

2.72 ± 0.94

2.76 ± 0.64

0.97

hsCRP (mg/L)

12.32 ± 53.46

11.68 ± 38.48

4.89 ± 9.30

<0.05

Type of AMI, n (%)

 

<0.05

STEMI

33 (78.6)

51 (45.5)

  

NSTEMI

9 (21.4)

61 (54.5)

  

BNP

1,670.71 ± 1,074.44a

433.72 ± 285.67a

60.69 ± 36.98

<0.05

LVEF

28.43 ± 4.79a

47.31 ± 7.69a

57.42 ± 6.28

<0.05

LVMI

90.51 ± 14.39a

70.43 ± 12.04a

82.67 ± 20.05

<0.05

LVEDD

61.95 ± 4.80a

49.45 ± 4.72a

50.23 ± 5.98

<0.05

LVESD

38.05 ± 5.73a

31.37 ± 4.08a

30.37 ± 4.15

<0.05

Six-min walk test

171.07 ± 70.32a

465.13 ± 189.00a

 

<0.05

Plasma ADAMTS-7 levels

6.73 ± 2.47a

3.22 ± 2.05a

1.63 ± 1.58

<0.05

  1. aMean P < 0.05 compared between the LVEF ≤35 group and LVEF >35% group; bmean comparison between the three groups. ADAMTS, a disintegrin and metalloproteinase with thrombospondin motifs; AMI, acute myocardial infarction; BMI, body mass index; HDL, high-density lipoprotein; LDL, low-density lipoprotein; hsCRP, high-sensitivity C-reactive protein; STEMI, ST-elevation myocardial infarction; NSTEMI, non-ST-elevation myocardial infarction; BNP, brain natriuretic peptide; LVEF, left ventricular ejection fraction; LVMI, left ventricular mass index; LVEDD, left ventricular end-diastolic diameter; LVESD, left ventricular end-systolic diameter.