| |
F1 and F2
|
F3 and F4
|
OR (95% CI)
|
P
value
|
|---|
NOX4 (rs3017887) |
N = 105 |
N = 73 | 0.60 (0.22 to 1.59) | 0.31 |
CC | 0.532 | 0.588 | | |
CA | 0.457 | 0.372 | | |
AA | 0.011 | 0.040 | | |
MAF | 0.239 | 0.226 | | |
CYBA (675 T → A) | | | 0.29 (0.06 to 1.11) | 0.09 |
TT | 0.800 | 0.882 | | |
TA | 0.190 | 0.118 | | |
AA | 0.010 | 0.000 | | |
MAF | 0.105 | 0.059 | | |
- Genotype frequencies of NOX4 rs3017887 and of CYBA −675 T → A (unregistered) single nucleotide polymorphisms by fibrosis grade in patients with chronic hepatitis C. Odds ratio (OR) and 95% confidence interval (95% CI) for the minor allele of the genotyped SNPs in a dominant model of logistic regression analysis adjusted for age, gender, metabolic syndrome status, triglycerides, plasmatic albumin concentrations, and HCV genotype. MAF, minor allele frequency (frequency of the rarer allele, A for both SNPs).
