Association of a variant in the regulatory region of NADPH oxidase 4 gene and metabolic syndrome in patients with chronic hepatitis C

Table 4 Genotype frequencies of NOX4 rs3017887 single nucleotide polymorphism by metabolic syndrome (MS) status

*NOX4* (rs3017887)	Absence of MS	Presence of MS	OR (95% CI)	P value
Female	(N = 63)	(N = 25)	1.71 (0.48 to 6.00)	0.40
CC	0.540	0.476
CA	0.440	0.524
AA	0.020	0.000
MAF	0.240	0.321
Male	(N = 66)	(N = 17)	0.15 (0.03 to 0.79)	0.025
CC	0.545	0.714
CA	0.436	0.286
AA	0.018	0.000
MAF	0.236	0.143

Genotype frequencies of NOX4 rs3017887 single nucleotide polymorphism by metabolic syndrome (MS) status in patients with chronic hepatitis C. Odds ratio (OR) and 95% confidence interval (95% CI) for the minor allele of rs3017887 SNP in a dominant model of logistic regression analysis adjusted for age, gender, type 2 diabetes status, body mass index and HCV genotype. MAF, minor allele frequency (frequency of the rarer allele, A for both SNPs).

ISSN: 2047-783X