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Figure 5 | European Journal of Medical Research

Figure 5

From: microRNA-98 mediated microvascular hyperpermeability during burn shock phase via inhibiting FIH-1

Figure 5

Co-silenced FIH-1 abrogated silenced miR-98-reduced permeability in rat aorta endothelial cells. Cells were pretreated with siRNA-FIH-1 followed by transfection with miR-98 inhibitor. After 48 h, the cells were incubated with burn serum or control serum. (A) Profiles of protein were determined using Western blot. (B) Transendothelial electrical resistance and (C) permeability coefficient of albumin were performed with monolayer endothelial cells. The data were represented as mean ± SD. * P < 0.05 compared with control plasma; # P < 0.05 compared with burn serum; *# P < 0.05 compared with burn serum + miR-98 inhibitor.

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