Table 1 Clinical profile, risk factors and preoperative therapy of the patients
From: Rapamycin impairs endothelial cell function in human internal thoracic arteries
Organ bath on ITA rings | Western blot on ITA homogenates | ||||
|---|---|---|---|---|---|
NA and Ach | m-TOR | p-mTOR | Akt | p-Akt | |
Age (years) | 64 (56–84) | 62 (56–68) | 64 (56–71) | 68 (54–81) | 68 (54–81) |
Number of patients (n) | 21 | 6 | 6 | 19 | 24 |
n (%) | n (%) | n (%) | n (%) | n (%) | |
Smokers | 6 (29) | 2 (33) | 2 (33) | 5 (26) | 9 (38) |
Hypercholesterinemia | 13 (62) | 2 (33) | 2 (33) | 11 (58) | 17 (71) |
Arterial hypertension | 11 (52) | 4 (67) | 5 (83) | 14 (74) | 16 (67) |
Diabetes mellitus | 2 (10) | 0 | 1 (17) | 9 (47) | 9 (38) |
Aspirin | 12 (57) | 5 (83) | 6 (100) | 17 (89) | 20 (83) |
Statine | 14 (67) | 6 (100) | 6 (100) | 15 (79) | 21 (88) |
Beta-blocker | 14 (67) | 4 (67) | 4 (67) | 15 (79) | 18 (75) |
ACE inhibitors | 4 (19) | 2 (33) | 2 (33) | 12 (63) | 16 (67) |
Calcium entry blockers | 1 (5) | 0 | 1 (17) | 3 (16) | 7 (29) |