Table 1 Characteristics of 70 patients diagnosed with large-cell neuroendocrine carcinoma of the lung
Factor | LCNEC (n = 70) |
|---|---|
Sex | |
Male | 52 (72 %) |
Female | 18 (28 %) |
Median age (range) | 63 years (41–81) |
Over 70 years | 20 (29 %) |
Under 70 years or 70 years | 50 (71 %) |
TNM stage (7th classification) | |
IA/IB | 9/10 |
IIA/IIB | 15/9 |
IIIA/IIIB | 18/2 |
IVA/IVB | 7 |
Thoracic surgery | 66 (94 %) |
Primary | 65 (93 %) |
Wedge resection | 4 (6 %) |
Lobectomy | 53 (81 %) |
Bilobectomy | 3 (5 %) |
Pneumonectomy | 5 (8 %) |
Chemotherapy | 36 (51 %) |
Definitive | 4 (6 %) |
Adjuvant | 32 (46 %) |
Relapse/progress | 14 (20 %) |
Thoracic radiotherapy | 17 (24 %) |
Definitive | 4 (6 %) |
Adjuvant/additive | 10 (14 %) |
Relapse/progress | 3 (4 %) |
First line therapy brain metastases | 17 (24 %) |
Resection | 7 (10 %) |
Stereotactic irradiation | 2 (3 %) |
Whole brain irradiation | 6 (9 %) |
Best supportive care | 2 (3 %) |
Prophylactic cranial irradiation (PCI) | 3 (4 %) |