From: An update on the clinical diagnostic value of β-hCG and αFP for intracranial germ cell tumors
Items | Past group (n = 32) | Recent group (n = 26) | |||
---|---|---|---|---|---|
Patients demographics | |||||
Sex ratio (male:female) | 17:15 (1.1:1) | 17:9 (1.9:1) | |||
Age at diagnosis (years), mean ± SD (range)* | 19 ± 6.9 (9–41) | 12.7 ± 4.3 (6–24) | |||
Tumor characteristics | |||||
Pathological classification, n (%) | Germinoma | 31 (90.6) | 17 (65.4) | ||
NGGCTs | 0 (0) | 2 (7.7) | |||
Mixed type | 1 (9.4) | 7 (26.9) | |||
Tumor location, n (%)a | Pineal | 1 (3.1) | 4 (15.3) | ||
Sellar | 19 (59.4) | 10 (38.5) | |||
Basal Ganglia | 4 (12.5) | 6 (23.1) | |||
Mixed type | 8 (25) | 6 (23.1) | |||
M staging (cases) | M0 (22/16) | M1 (4/1) | M2 (4/9) | M3 (2/0) | M4 (0/0) |
Method of confirmation | |||||
CSF cytology, n (%) | Total cases | 14 (43.8) | 26 (100) | ||
Positive | 9 (64.3) | 1 (3.8) |
Surgical resection | Germinoma | NGGCTs | Mixed type | Total | |
---|---|---|---|---|---|
Biopsy | 8/16 | 0/0 | 0/2 | 8/18 | |
PR | 7/0 | 0/0 | 1/1 | 8/1 | |
STR | 7/1 | 0/2 | 0/1 | 7/4 | |
GTR | 0/0 | 0/0 | 0/2 | 0/2 | |
No surgery | 9/1 | 0/0 | 0/0 | 9/1 | |
History of radiography (cases) | 0/1 | 0/1 | 0/1 | 0/3 |