Skip to main content

Table 1 Randomised, controlled trials of vitamin D for treatment of active tuberculosis

From: Vitamin D and airway infections: a European perspective

Author (ref.)

Publication year

N (total)

Age (years)

Initial 25OHD (nmol/l)

In-study 25OHD (nmol/l)

Mean vitamin D dose (IU)

Duration

Endpoint

Vit D

Placebo

Vit D

Placebo

Nursyam [39]

2006

67

31

ND

ND

ND

ND

10,000 daily

6 weeks

Sputum conversion

Wejse [40]

2009

365

37

77

79

98

95

100,000 quarterly

12 months

Sputum conversion

Martineau [41]

2011

146

31

21

21

101

23

4 × 100,000

6 days

Sputum conversion

Salahuddin [42]

2013

259

28

52

58

220

50

2 × 600,000

12 weeks

Sputum conversion

Ralph [43]

2013

200

28

ND

ND

ND

ND

50,000 monthly

8 weeks

Sputum conversion

Daley [44]

2015

247

43

58

54

72

60

100,000 quarterly

12 months

Sputum conversion

  1. 25OHD 25-hydroxyvitamin D; IU international units; ND not determined