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Table 1 Randomised, controlled trials of vitamin D for treatment of active tuberculosis

From: Vitamin D and airway infections: a European perspective

Author (ref.) Publication year N (total) Age (years) Initial 25OHD (nmol/l) In-study 25OHD (nmol/l) Mean vitamin D dose (IU) Duration Endpoint
Vit D Placebo Vit D Placebo
Nursyam [39] 2006 67 31 ND ND ND ND 10,000 daily 6 weeks Sputum conversion
Wejse [40] 2009 365 37 77 79 98 95 100,000 quarterly 12 months Sputum conversion
Martineau [41] 2011 146 31 21 21 101 23 4 × 100,000 6 days Sputum conversion
Salahuddin [42] 2013 259 28 52 58 220 50 2 × 600,000 12 weeks Sputum conversion
Ralph [43] 2013 200 28 ND ND ND ND 50,000 monthly 8 weeks Sputum conversion
Daley [44] 2015 247 43 58 54 72 60 100,000 quarterly 12 months Sputum conversion
  1. 25OHD 25-hydroxyvitamin D; IU international units; ND not determined