Skip to main content

Table 10 Association of glutathione peroxidase activity in relation to CYP1A1 and GST gene polymorphisms in NSCLC patients and healthy controls

From: Association of CYP1A1, GSTM1 and GSTT1 gene polymorphisms with risk of non-small cell lung cancer in Andhra Pradesh region of South India

Gene Genotype Lung cancer patients (GPx levels) p value Controls (GPx levels) p value Total p value
n Mean ± SE n Mean ± SE
CYP1A1 m1 T/T 121 47.51 ± 4.52   138 55.44 ± 0.60   <0.01*
  T/C 89 45.77 ± 2.45 0.01* 98 55.15 ± 0.69 0.74 <0.01*
  C/C 28 43.42 ± 2.02 <0.01* 14 51.42 ± 1.74 0.79 0.06
CYP1A1 m2 A/A 71 48.18 ± 6.45   196 59.35 ± 0.33   <0.01*
  A/G 156 44.02 ± 1.75 <0.01* 34 55.26 ± 0.65 0.17 <0.02*
  G/G 11 45.94 ± 2.93 0.01* 20 54.67 ± 0.91 0.53 <0.01*
GSTM1 +/+ 174 46.22 ± 1.74   187 57.69 ± 0.36   <0.01*
  –/– 64 40.87 ± 2.69 0.33 63 54.41 ± 0.84 0.21 <0.01*
GSTT1 +/+ 192 46.66 ± 1.53   224 55.50 ± 0.47   <0.001*
  –/– 46 36.95 ± 3.95 0.05* 26 51.69 ± 1.12 0.07 <0.001*
  1. * p < 0.05