Association of CYP1A1, GSTM1 and GSTT1 gene polymorphisms with risk of non-small cell lung cancer in Andhra Pradesh region of South India

Table 13 Multiple regression analysis of different variants in NSCLC

Variable	Unstandardised coeeficients		Standardized coefficients	t	Sig.	95 % confidence interval for B
	Unstandardised coeeficients					Lower bound	Upper bound
	B ^a	Standard error^b				Lower bound	Upper bound
Age	0.001	0.001	0.012	1.241	0.216	0.000	0.002
Sex	−0.017	0.014	−0.015	−1.245	0.215	−0.044	0.010
Smoking	−0.005	0.008	−0.009	−0.624	0.034*	−0.021	0.011
Passive smoking	−0.003	0.018	−0.002	−0.165	0.869	−0.038	0.032
Histology	−0.049	0.009	−0.094	−5.402	0.000*	−0.067	−0.031
Stage	−0.173	0.017	−0.463	−9.935	0.000*	−0.207	−0.138
Alcohol	0.007	0.011	0.007	0.639	0.523	−0.015	0.030
Diet	−0.001	0.013	−0.001	−0.063	0.950	−0.026	0.025
Place of living	−0.004	0.006	−0.007	−0.666	0.506	−0.015	0.007
Familial	−0.018	0.023	−0.008	−0.769	0.443	−0.063	0.027
MDA	0.026	0.013	0.083	1.991	0.048*	0.000	0.052
GPx	−0.005	0.001	−0.199	−9.468	0.000*	−0.006	−0.004
SOD	−0.005	0.000	0.012	0.494	0.622	0.000	0.000
8-OHdG	0.019	0.012	0.045	1.622	0.106	−0.004	0.043
CYPM1	−0.003	0.007	−0.003	−0.376	0.007*	−0.016	0.011
CYPM2	−0.002	0.008	−0.003	−0.268	0.789	−0.019	0.014
GSTM1	−0.008	0.015	−0.006	−0.512	0.609	−0.037	0.022
GSTT1	−0.020	0.018	−0.014	−1.072	0.025*	−0.056	0.017

ISSN: 2047-783X