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Table 1 Relationship of CDK5 expression with other clinicopathological variables

From: Evaluation and clinical significance of cyclin-dependent kinase5 expression in cervical lesions: a clinical research study in Guangxi, China

Characteristic Total number No. patients, stratified by CDK5 Z P value
Negative (228) Positive (266)
Age     −1.557 0.120a
 ≤44 263 130 (49.4 %) 133 (50.6 %)   
 >44 231 98 (42.4 %) 133 (57.6 %)   
Lymph node metastasis     −5.998 <0.001a
 Negative 264 128 (48.5 %) 136 (51.5 %)   
 Positive 96 13 (13.5 %) 83 (86.5 %)   
Histological type     32.490 <0.001b
 Chronic cervicitis 54 39 (72.2 %) 15 (27.8 %)   
 CA 42 29 (69.0 %) 13 (31.0 %)   
 Carcinoma in situ 38 19 (50.0 %) 19 (50.0 %)   
 Adenocarcinoma 63 29 (46.0 %) 34 (54.0 %)   
 SCC 263 98 (37.3 %) 165 (62.7 %)   
 Adenosquamous carcinoma 34 14 (41.2 %) 20 (58.8 %)   
FIGO stage     −5.998 <0.001a
 I–II 264 128 (48.5 %) 136 (51.5 %)   
 III–IV 96 13 (13.5 %) 83 (86.5 %)   
TNM stage     52.911 <0.001b
 0 38 19 (50.0 %) 19 (50.0 %)   
 I 248 128 (51.6 %) 120 (48.4 %)   
 II–IV 112 13 (11.6 %) 99 (88.4 %)   
Pathological grade     23.604 <0.001b
 I 28 16 (57.1 %) 12 (42.9 %)   
 II 157 77 (49.0 %) 80 (51.0 %)   
 III 141 34 (24.1 %) 107 (75.9 %)   
  1. CA condyloma acuminates, SCC squamous cell carcinoma, FIGO International Federation of Gynecology and Obstetrics, TNM tumor node metastasis
  2. aTwo independent-samples Chi-square test was performed
  3. bKruskal–Wallis H test was performed