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Table 1 Relationship of CDK5 expression with other clinicopathological variables

From: Evaluation and clinical significance of cyclin-dependent kinase5 expression in cervical lesions: a clinical research study in Guangxi, China

Characteristic

Total number

No. patients, stratified by CDK5

Z

P value

Negative (228)

Positive (266)

Age

   

−1.557

0.120a

 ≤44

263

130 (49.4 %)

133 (50.6 %)

  

 >44

231

98 (42.4 %)

133 (57.6 %)

  

Lymph node metastasis

   

−5.998

<0.001a

 Negative

264

128 (48.5 %)

136 (51.5 %)

  

 Positive

96

13 (13.5 %)

83 (86.5 %)

  

Histological type

   

32.490

<0.001b

 Chronic cervicitis

54

39 (72.2 %)

15 (27.8 %)

  

 CA

42

29 (69.0 %)

13 (31.0 %)

  

 Carcinoma in situ

38

19 (50.0 %)

19 (50.0 %)

  

 Adenocarcinoma

63

29 (46.0 %)

34 (54.0 %)

  

 SCC

263

98 (37.3 %)

165 (62.7 %)

  

 Adenosquamous carcinoma

34

14 (41.2 %)

20 (58.8 %)

  

FIGO stage

   

−5.998

<0.001a

 I–II

264

128 (48.5 %)

136 (51.5 %)

  

 III–IV

96

13 (13.5 %)

83 (86.5 %)

  

TNM stage

   

52.911

<0.001b

 0

38

19 (50.0 %)

19 (50.0 %)

  

 I

248

128 (51.6 %)

120 (48.4 %)

  

 II–IV

112

13 (11.6 %)

99 (88.4 %)

  

Pathological grade

   

23.604

<0.001b

 I

28

16 (57.1 %)

12 (42.9 %)

  

 II

157

77 (49.0 %)

80 (51.0 %)

  

 III

141

34 (24.1 %)

107 (75.9 %)

  
  1. CA condyloma acuminates, SCC squamous cell carcinoma, FIGO International Federation of Gynecology and Obstetrics, TNM tumor node metastasis
  2. aTwo independent-samples Chi-square test was performed
  3. bKruskal–Wallis H test was performed