Fig. 5

Distribution of mutations according to actual address of patients 19–33. Each circle represents a patient carrying one specific mutation (homozygous) or two (compound heterozygous), according to the colors in the caption. AC Acre, AL Alagoas, AM Amazonas, AP Amapá, BA Bahia, CE Ceará, ES Espírito Santo, GO Goiás, MA Maranhão, MG Minas Gerais, MS Mato Grosso do Sul, MT Mato Grosso, PA Pará, PB Paraíba, PE Pernambuco, PI Piauí, PR Paraná, RJ Rio de Janeiro, RN Rio Grande do Norte, RO Rondônia, RR Roraima, RS Rio Grande do Sul, SC Santa Catarina, SE Sergipe, SP São Paulo, TO Tocantins. More information about patients’ origin and precedence is available in Additional file 3