Fig. 1

The cytokine profile measured by multiplex immunoassay. The multiple cytokines were measured by Multiplex Immunoassay Kit (Affymetrix, CA, USA) for the concentration of 18 cytokines (IL-10, IL-17A, IL-21, IL-22, IL-23, IL-27, IL-9, GM-CSF, IFN-γ, IL-1b, IL-12, P70, IL-13, IL-18, IL-2, IL-4, IL-5, IL-6, TNF-α). Among all the 18 screened cytokines, three cytokines IL-12, IL-18 and IFN-γ showed the significant increase and diagnostic value