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Table 8 Value of synovial biopsy

From: Prosthetic joint infection development of an evidence-based diagnostic algorithm

Author

Year

LoE

CoR

(n = x)

Sensitivity

Specifity

Positive predictive value

Negative predictive value

LR for a positive result

LR for a negative result

Banit et al.

2002

I

I

       

 Frozen section (Hip)

   

63

0.45 (0.16–0.75)

0.92 (0.85–1.0)

0.56 (0.23–0.88)

0.89 (0.81–0.97)

5.91 (1.07–166.5)

0.59 (0.25–0.99)

 Frozen section (knee)

   

55

1

0.96 (0.9–1.0)

0.82 (0.59–1.0)

1

23.00 (9.76–64.7)

0

 (Knee + hip.shoulder)

   

121

0.67 (0.48–0.86)

0.95 (0.91–1.0)

0.8 (0.62–0.98)

0.91 (0.86–0.97)

14.67 (5.37–442)

0.35 (0.15–0.57)

Borrego et al.

2007

I

I

       

 Frozen sectio (Hip)

   

83

0.5 (0.15–0.85)

1

1

0.95 (0.9–1.0)

X

0.5 (0.15–0.85)

 Frozen section (knee)

   

63

0.67 (0.48–0.86)

0.9 (0.8–0.99)

0.8 (0.62–0.98)

0.81 (0.7–0.93)

6.5 (2.42–116.4)

0.37 (0.15–0.65)

Schinsky et al.

2008

I

I

201

      

 Frozen section

    

0.73 (0.61–0.84)

0.94 (0.9–0.98)

0.82 (0.71–0.92)

0.9 (0.85–0.95)

11.8 (6.06–37.34)

0.29 (0.16–0.43)

Fink et al.

2008

I

I

145

      

 Fixed section (knee)

    

1

0.98 (0.95–1.0)

0.95 (0.89–1.0)

1

52.5 (22.13–140.88)

X

 Tissue culture (knee)

    

0.78 (0.65–0.9)

0.98 (0.95–1.0)

0.94 (0.86–1.0)

0.92 (0.87–0.97)

40.69 (14.28–127.41)

0.23 (0.09–0.37)

 Both

    

0.78 (0.65–0.9)

0.98 (0.95–1.0)

0.94 (0.86–1.0)

0.92 (0.87–0.97)

40.69 (14.28–127.41)

0.23 (0.09–0.37)

Della Valle et al.

2007

I

I

94

      

 Forzen section

    

0.88 (0.78–0.98)

0.96 (0.91–1.0)

0.95 (0.88–1.0)

0.91 (0.84–0.99)

23.27 (8.74–72.1)

0.13 (0.02–0.24)

Fink et al.

2013

I

I

100

      

 Fixed section (hip)

    

0.62 (0.48–0.76)

1

1

0.76 (0.67–0.86)

X

0.38 (0.24–0.52)

 Tissue culture (hip)

    

0.73 (0.6–0.86)

0.98 (0.95–1.0)

0.97 (0.91–1.0)

0.82 (0.73–0.91)

40.33 (11.29–50.36)

0.27 (0.14–0.42)

 Both

    

0.82 (0.71–0.93)

0.98 (0.95–1.0)

0.97 (0.92–1.0)

0.87 (0.06–0.31)

45.22 (13.28–54.52)

0.18 (0.06–0.31)