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Table 2 Diagnostic value of different diagnostic tools and their combinations for diagnosis of PJI of the hip

From: Diagnostic accuracy of arthroscopic biopsy in periprosthetic infections of the hip

  Aspiration (microbiology) Aspiration (cell count/percentage neutrophiles) Arthroscop. biopsy (microbiology) Arthroscop. biopsy (microbiology + histology) ESR CRP Aspiration (ESR + cell count/percentage neutrophiles) Aspiration (CRP + cell count/percentage neutrophiles) Aspiration (ESR + CRP + cell count/percentage neutrophiles + microbiology)
Sensitivity (95% CI in %) 50.0% (15.7–84.3) 80.0% (28.4–99.5) 75.0% (34.9–96.8) 87.5% (47.7–99.7) 75.0% (19.4–99.4) 75.0% (34.9–96.8) 75.0% (19.4–99.4) 80.0% (28.4–99.5) 87.5% (47.7–99.7)
Specificity (95% CI in %) 91.7% (61.5–99.8) 60.0% (14.7–94.7) 83.3% (51.6–97.9) 100% (73,5–100) 87.5% (47.4–99.7) 66.7% (34.9–90.1) 100% (29.2–100) 80,0% (28.4–99.5) 91.7% (61.5–99.8)
PPV (95% CI in %) 80.0% (28.4–99.5) 66.7% (22.3–95.7) 75.0% (44.3–91.9) 100% (59.0–100) 75.0% (19.4–99.4) 60.0% (26.2–87.8) 100% (29.2–100) 80.0% (28.4–99.5) 87.5% (47.7–99.7)
NPV (95% CI in %) 73.3% (44.9–92.2) 75.0% (19.4–99.4) 83.3 (59.5–94.5) 92% (64.0–99.8) 87.5% (47.4–99.7) 80.0% (44.4–97.5) 75.0% (19.4–99.4) 80.0% (28.4–99.5) 91.7% (61.5–99.8)
LR+ (95% CI) 6.00 (0.8–44.4) 2.00 (0.6–6.4) 4.50 (1.2–17.0) 21.70 (1.4–333.4) 6.00 (0.9–40.9) 2.25 (0.9–5.5) 5.60 (0.4–79.7) 4.00 (0.7–24.4) 10.50 (1.6–69.8)
LR− (95% CI) 0.55 (0.3–1.1) 0.33 (0.05–2.2) 0.30 (0.09–1.02) 0.17 (0.04–0.8) 0.29 (0.05–1.6) 0.38 (0.1–1.3) 0.34 (0.09–1.4) 0.25 (0.04–1.5) 0.14 (0.02–0.9)
Accuracy 75% 70% 80% 95% 83% 70% 86% 80% 90%