Table 2 Diagnostic value of different diagnostic tools and their combinations for diagnosis of PJI of the hip
From: Diagnostic accuracy of arthroscopic biopsy in periprosthetic infections of the hip
Aspiration (microbiology) | Aspiration (cell count/percentage neutrophiles) | Arthroscop. biopsy (microbiology) | Arthroscop. biopsy (microbiology + histology) | ESR | CRP | Aspiration (ESR + cell count/percentage neutrophiles) | Aspiration (CRP + cell count/percentage neutrophiles) | Aspiration (ESR + CRP + cell count/percentage neutrophiles + microbiology) | |
|---|---|---|---|---|---|---|---|---|---|
Sensitivity (95% CI in %) | 50.0% (15.7–84.3) | 80.0% (28.4–99.5) | 75.0% (34.9–96.8) | 87.5% (47.7–99.7) | 75.0% (19.4–99.4) | 75.0% (34.9–96.8) | 75.0% (19.4–99.4) | 80.0% (28.4–99.5) | 87.5% (47.7–99.7) |
Specificity (95% CI in %) | 91.7% (61.5–99.8) | 60.0% (14.7–94.7) | 83.3% (51.6–97.9) | 100% (73,5–100) | 87.5% (47.4–99.7) | 66.7% (34.9–90.1) | 100% (29.2–100) | 80,0% (28.4–99.5) | 91.7% (61.5–99.8) |
PPV (95% CI in %) | 80.0% (28.4–99.5) | 66.7% (22.3–95.7) | 75.0% (44.3–91.9) | 100% (59.0–100) | 75.0% (19.4–99.4) | 60.0% (26.2–87.8) | 100% (29.2–100) | 80.0% (28.4–99.5) | 87.5% (47.7–99.7) |
NPV (95% CI in %) | 73.3% (44.9–92.2) | 75.0% (19.4–99.4) | 83.3 (59.5–94.5) | 92% (64.0–99.8) | 87.5% (47.4–99.7) | 80.0% (44.4–97.5) | 75.0% (19.4–99.4) | 80.0% (28.4–99.5) | 91.7% (61.5–99.8) |
LR+ (95% CI) | 6.00 (0.8–44.4) | 2.00 (0.6–6.4) | 4.50 (1.2–17.0) | 21.70 (1.4–333.4) | 6.00 (0.9–40.9) | 2.25 (0.9–5.5) | 5.60 (0.4–79.7) | 4.00 (0.7–24.4) | 10.50 (1.6–69.8) |
LR− (95% CI) | 0.55 (0.3–1.1) | 0.33 (0.05–2.2) | 0.30 (0.09–1.02) | 0.17 (0.04–0.8) | 0.29 (0.05–1.6) | 0.38 (0.1–1.3) | 0.34 (0.09–1.4) | 0.25 (0.04–1.5) | 0.14 (0.02–0.9) |
Accuracy | 75% | 70% | 80% | 95% | 83% | 70% | 86% | 80% | 90% |