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Table 1 The changes of lung coefficient, the contents of IL-1β, IL-6, and TNF-α in the plasma and lung tissue from limb I/R-induced ALI rats with different treatments

From: Role of carbonyl sulfide in acute lung injury following limb ischemia/reperfusion in rats

Group

LW/BW (g/kg)

IL-1β

IL-6

TNF-a

Blood

Lung

Blood

Lung

Blood

Lung

Control

4.91 ± 0.42

25.89 ± 3.66

29.13 ± 4.87

68.22 ± 3.45

63.76 ± 3.86

164.58 ± 11.57

166.13 ± 9.18

I/R

5.95 ± 0.45*

100.60 ± 4.55*

507.47 ± 42.88*

3161.75 ± 207.19*

3095.14 ± 133.31*

2140.42 ± 83.49*

2201.68 ± 110.98*

I/R + 0.2 COS

5.03 ± 0.34#

66.97 ± 3.05#

105.58 ± 7.00#

448.89 ± 38.09#

449.07 ± 35.90#

1096.32 ± 68.80#

1108.18 ± 83.42#

I/R + 0.5 COS

5.1 ± 0.28#

70.16 ± 6.81#

126.77 ± 7.29#

557.01 ± 46.16#

543.93 ± 50.08#

1273.14 ± 121.44#

1274.66 ± 77.39#

I/R + 1.0 COS

5.58 ± 0.26#

77.95 ± 4.53#

387.89 ± 16.94#

2505.43 ± 310.50#

2500.55 ± 252.13#

1664.40 ± 46.01#

1670.88 ± 46.86#

I/R + 0.4 AIR

5.61 ± 0.29

100.30 ± 3.75

510.30 ± 17.02

3121.37 ± 298.35

3106.05 ± 169.37

2181.87 ± 128.33

2205.22 ± 156.34

I/R + 1.0 AIR

5.56 ± 0.34

100.96 ± 2.92

498.63 ± 20.41

2976.81 ± 261.15

3102.09 ± 218.91

2106.59 ± 137.97

2096.89 ± 166.49

I/R + 2.0 AIR

5.6 ± 0.39

98.66 ± 5.08

490.28 ± 16.71

3152.10 ± 220.3

3125.53 ± 153.9

2163.42 ± 164.04

2164.85 ± 118.42

  1. Mean ± SD. n = 8
  2. * p < 0.01 vs. control group, # p < 0.01 vs. I/R group, p < 0.05 vs. I/R + AIR group