From: Role of carbonyl sulfide in acute lung injury following limb ischemia/reperfusion in rats
Group | LW/BW (g/kg) | IL-1β | IL-6 | TNF-a | |||
---|---|---|---|---|---|---|---|
Blood | Lung | Blood | Lung | Blood | Lung | ||
Control | 4.91 ± 0.42 | 25.89 ± 3.66 | 29.13 ± 4.87 | 68.22 ± 3.45 | 63.76 ± 3.86 | 164.58 ± 11.57 | 166.13 ± 9.18 |
I/R | 5.95 ± 0.45* | 100.60 ± 4.55* | 507.47 ± 42.88* | 3161.75 ± 207.19* | 3095.14 ± 133.31* | 2140.42 ± 83.49* | 2201.68 ± 110.98* |
I/R + 0.2 COS | 5.03 ± 0.34#△ | 66.97 ± 3.05#△ | 105.58 ± 7.00#△ | 448.89 ± 38.09#△ | 449.07 ± 35.90#△ | 1096.32 ± 68.80#△ | 1108.18 ± 83.42#△ |
I/R + 0.5 COS | 5.1 ± 0.28#△ | 70.16 ± 6.81#△ | 126.77 ± 7.29#△ | 557.01 ± 46.16#△ | 543.93 ± 50.08#△ | 1273.14 ± 121.44#△ | 1274.66 ± 77.39#△ |
I/R + 1.0 COS | 5.58 ± 0.26#△ | 77.95 ± 4.53#△ | 387.89 ± 16.94#△ | 2505.43 ± 310.50#△ | 2500.55 ± 252.13#△ | 1664.40 ± 46.01#△ | 1670.88 ± 46.86#△ |
I/R + 0.4 AIR | 5.61 ± 0.29 | 100.30 ± 3.75 | 510.30 ± 17.02 | 3121.37 ± 298.35 | 3106.05 ± 169.37 | 2181.87 ± 128.33 | 2205.22 ± 156.34 |
I/R + 1.0 AIR | 5.56 ± 0.34 | 100.96 ± 2.92 | 498.63 ± 20.41 | 2976.81 ± 261.15 | 3102.09 ± 218.91 | 2106.59 ± 137.97 | 2096.89 ± 166.49 |
I/R + 2.0 AIR | 5.6 ± 0.39 | 98.66 ± 5.08 | 490.28 ± 16.71 | 3152.10 ± 220.3 | 3125.53 ± 153.9 | 2163.42 ± 164.04 | 2164.85 ± 118.42 |