Table 1 Basal characteristics of Isfahani adult people (n = 615) with newly thyroid function in 2011 were euthyroid in 2006
|  | Euthyroid, n (%) | Subclinical hypothyroidism, n (%) | OR (CI 95%) | Overt hypothyroidism, n (%) | OR (CI 95%) | Overt + subclinical hypothyroidism, n (%) | OR (CI 95%) | Subclinical hyperthyroidism, n (%) | OR (CI 95%) | Overt hyperthyroidism, n (%) | OR (CI 95%) | Overt + subclinical hyperthyroidism, n (%) | OR (CI 95%) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sex | |||||||||||||
 Men | 281 (54.1) | 27 (37.5) | 1.96 (1.18–3.26)* | 4 (44.4) | 1.47 (0.39–5.55) | 31 (38.3) | 1.90 (1.17–3.07)* | 2 (20) | 4.7 (0.99–22.45)* | 0 (0) |  | 2 (13.3) | 7.67 (1.17–34.34)* |
 Women | 238 (45.9) | 45 (62.5) | 5 (55.6) | 50 (61.7) | 8 (80) | 5 (100) | 13 (86.6) | ||||||
Age (years) | |||||||||||||
 20–40 | 153 (29.7) | 14 (19.4) | 1 | 4 (44.4) | 1 | 18 (22.2) | 1 | 4 (40) | 1 | 2 (40) | 1 | 6 (40) | 1 |
 40–60 | 274 (53.2) | 42 (58.3) | 1.67 (0.88–3.16) | 2 (22.2) | 0.27 (0.05–1.54) | 44 (54.3) | 1.36 (0.76–2.44) | 5 (50) | 0.69 (0.18–2.63) | 2 (40) | 0.55 (0.07–4.00) | 7 (46.7) | 0.65 (0.21–1.97) |
 ≥60 | 88 (17.1) | 16 (22.2) | 1.98 (0.92–4.26) | 3 (33.3) | 1.3 (0.28–5.96) | 19 (23.5) | 1.83 (0.91–3.68) | 1 (10) | 0.43 (0.04–3.95) | 1 (20) | 0.86 (0.07–9.7) | 2 (13.3) | 0.58 (0.11–2.93) |
BMI (kg/m2) | |||||||||||||
 <25 | 151 (29.9) | 22 (31.4) | 1 | 2 (22.2) | 1 | 24 (30.4) | 1 | 0 (0) | 1 | 3 (60) | 1 | 3 (20) | 1 |
 25–30 | 230 (45.5) | 27 (38.6) | 0.8 (0.44–1.46) | 3 (33.3) | 0.98 (0.16–5.96) | 30 (38.0) | 0.82 (0.46–1.45) | 5 (50) |  | 1 (20) | 0.21 (0.02–2.12) | 6 (40) | 1.31 (0.32–5.33) |
 ≥30 | 124 (24.6) | 21 (30) | 1.1 (0.61–2.21) | 4 (44.4) | 2.43 (0.43–16.51) | 25 (31.6) | 1.26 (0.69–2.33) | 5 (50) |  | 1 (20) | 0.40 (0.04–3.95) | 6 (40) | 2.43 (0.59–9.93) |
FPG (mg/d) | |||||||||||||
 <100 | 289 (56.2) | 51 (70.8) | 1 | 7 (77.8) | 1 | 58 (71.6) | 1 | 7 (77.8) | 1 | 2 (40) | 1 | 9 (64.3) | 1 |
 100–126 | 176 (34.2) | 17 (23.6) | 0.54 (0.3–0.97)* | 1 (11.1) | 0.23 (0.02–1.92) | 18 (22.2) | 0.51 (0.29–0.89)* | 2 (22.2) | 0.46 (0.09–2.28) | 1 (20) | 0.82 (0.07–9.12) | 3 (21.4) | 0.54 (0. 14–2.04) |
 ≥126 | 49 (9.5) | 4 (5.6) | 0.46 (0.16–1.33) | 1 (11.1) | 0.84 (0.10–6.99) | 5 (6.2) | 0.5 (0.19–1.33) | 0 (0) |  | 2 (40) | 5.8 (0.81–42.85) | 2 (14.3) | 1.31 (0.27–6.24) |
Smoking | |||||||||||||
 Yes | 42 (8.1) | 4 (5.6) | 0.66 (0.23–1.92) | 1 (11.1) | 1.42 (0.17–11.62) | 5 (6.1) | 0.74 (0.28–1.94) | 1 (10) | 1.26 (0.15–10.2) | 0 (0) |  | 1 (6.7) | 0.81 (0.1–6.32) |
 No | 477 (91.9) | 68 (94.4) | 8 (88.9) | 76 (93.9) | 9 (90) | 5 (100) | 14 (93.3) | ||||||
Positive family history | |||||||||||||
 Yes | 132 (26.4) | 29 (40.8) | 1.92 (1.15–3.21)* | 2 (22.2) | 0.79 (0.16–3.88) | 31 (38.8) | 1.76 (1.07–2.88)* | 7 (77.8) | 9.75 (2.0–47.65)* | 2 (40) | 1.85 (0.30–11.24) | 9 (64.3) | 5 (1.65–15.24)* |
 No | 368 (73.6) | 42 (59.2) | 7 (77.8) | 49 (61.3) | 2 (22.2) | 3 (60) | 5 (35.7) | ||||||
TPOAb (IU/mL) | |||||||||||||
 Positive | 110 (23.4) | 27 (42.2) | 2.39 (1.39–4.11)* | 4 (50) | 3.2 (0.8–13.33) | 31 (43.1) | 2.48 (1.46–4.14)* | 8 (80) | 13.12 (2.74–62.72)* | 4 (80) | 13.12 (1.45–118.6)* | 12 (80) | 13.12 (3.63–47.35)* |
TgAb (IU/mL) | |||||||||||||
 Positive | 3 (9.4) | 2 (25) | 3.22 (0.43–23.65) | 1 (100) | 0 | 3 (33.3) | 4.83 (0.77–30) | 0 (0) |  | 0 (0) |  | 0 (0) |  |