Baseline | 6-month follow-up | |||||
---|---|---|---|---|---|---|
High Responder | Low Responder | p | High Responder | Low Responder | p | |
n = 20 | n = 25 | n = 20 | n = 25 | |||
PISA (mm/s ± SD) | 8 ± 2 | 8 ± 2 | 0.98 | 5 ± 1 | 5 ± 2 | 0.75 |
VC (mm ± SD) | 6 ± 2 | 6 ± 2 | 0.59 | 4 ± 2 | 4 ± 1 | 0.79 |
PAsys (mmHg ± SD) | 40 ± 14 | 36 ± 17 | 0.44 | 34 ± 11 | 35 ± 11 | 0.89 |
TAPSE (mm ± SD) | 18 ± 3 | 19 ± 5 | 0.83 | 20 ± 6 | 19 ± 6 | 0.60 |
LA area (cm2 ± SD) | 31 ± 9 | 29 ± 8 | 0.39 | 31 ± 7 | 29 ± 15 | 0.62 |
RA area (cm2 ± SD) | 26 ± 6 | 25 ± 9 | 0.67 | 24 ± 9 | 23 ± 8 | 0.54 |
LVEDD (mm ± SD) | 67 ± 10 | 57 ± 14 | 0.04 | 67 ± 11 | 61 ± 15 | 0.27 |
EF (% ± SD) | 31 ± 8 | 32 ± 8 | 0.62 | 32 ± 8 | 37 ± 10 | 0.22 |
PE | 0 | 0 | 0 | 0 | ||
Grade of MR | 0.86 | 0.92 | ||||
4+ | 14 | 19 | 0 | 0 | ||
3+ | 4 | 1 | 0 | 2 | ||
2+ | 2 | 5 | 6 | 6 | ||
1+ | 0 | 0 | 14 | 16 | ||
NT pro-BNP (pg/mL ± SD) | 2837 ± 1642 | 2070 ± 2605 | 0.43 | 1705 ± 1080 | 2782 ± 2632 | 0.22 |