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Table 2 Echocardiographic and functional values at baseline and at 6-month follow-up

From: Acute reverse annular remodeling during MitraClip® therapy predicts improved clinical outcome in heart failure patients: a 3D echocardiography study

  Baseline 6-month follow-up
High Responder Low Responder p High Responder Low Responder p
n = 20 n = 25 n = 20 n = 25
PISA (mm/s ± SD) 8 ± 2 8 ± 2 0.98 5 ± 1 5 ± 2 0.75
VC (mm ± SD) 6 ± 2 6 ± 2 0.59 4 ± 2 4 ± 1 0.79
PAsys (mmHg ± SD) 40 ± 14 36 ± 17 0.44 34 ± 11 35 ± 11 0.89
TAPSE (mm ± SD) 18 ± 3 19 ± 5 0.83 20 ± 6 19 ± 6 0.60
LA area (cm2 ± SD) 31 ± 9 29 ± 8 0.39 31 ± 7 29 ± 15 0.62
RA area (cm2 ± SD) 26 ± 6 25 ± 9 0.67 24 ± 9 23 ± 8 0.54
LVEDD (mm ± SD) 67 ± 10 57 ± 14 0.04 67 ± 11 61 ± 15 0.27
EF (% ± SD) 31 ± 8 32 ± 8 0.62 32 ± 8 37 ± 10 0.22
 PE 0 0   0 0  
Grade of MR    0.86    0.92
 4+ 14 19   0 0  
 3+ 4 1   0 2  
 2+ 2 5   6 6  
 1+ 0 0   14 16  
NT pro-BNP (pg/mL ± SD) 2837 ± 1642 2070 ± 2605 0.43 1705 ± 1080 2782 ± 2632 0.22
  1. EF ejection fraction, LA left atrial, LVEDD left ventricular end-diastolic diameter, MR mitral regurgitation, NT pro-BNP N-terminal pro b-type natriuretic peptide, PAsys systolic pulmonary artery pressure, PE pericardial effusion, PISA proximal isovelocity area, RA right atrial, TAPSE tricuspid annular plane systolic excursion, VC vena contracta