| |
Men
|
Women
|
|---|
|
No BMI change
|
BMI decrease
|
BMI increase
|
No BMI change
|
BMI decrease
|
BMI increase
|
|---|
|
N
|
4162 (65.7%)
|
1489 (23.5%)
|
685 (10.8%)
|
4651 (63.8%)
|
1634 (22.4%)
|
1010 (13.8%)
|
|
Age
|
58.65 ± 11.85
|
58.25 ± 11.70
|
58.53 ± 11.87
|
63.57 ± 11.57
|
63.41 ± 11.02
|
36.36 ± 11.09
|
|
BMI
|
29.73 ± 3.89
|
30.17 ± 4.32
|
29.98 ± 4.95
|
29.11 ± 4.73
|
30.38 ± 4.71
|
29.78 ± 5.10
|
|
SBP (mmHg)
|
140.45 ± 15.99
|
140.51 ± 17.35
|
140.02 ± 16.57
|
140.50 ± 16.16
|
140.98 ± 17.42*
|
140.35 ± 16.21
|
|
SBP at 12 months (mmHg)
|
132.94 ± 10.48*
|
131.06 ± 9.72*
|
134.41 ± 11.58*
|
131.21 ± 9.70*
|
130.21 ± 10.48*
|
132.36 ± 11.49*
|
|
DBP (mmHg)
|
85.21 ± 8.74*
|
85.02 ± 9.88*
|
84.75 ± 7.94*
|
84.89 ± 9.74*
|
84.93 ± 9.81
|
83.75 ± 9.79*
|
|
DBP at 12 months (mmHg)
|
80.43 ± 6.81*
|
80.25 ± 6.9*
|
82,19 ± 7,0*
|
79.59 ± 6.8*
|
78.83 ± 6.7*
|
80.55 ± 8.0*
|
|
Creatinine (μmol/l)
|
82.63 ± 18.90
|
81.78 ± 18.42
|
82.53 ± 18.09
|
81.78 ± 17.96
|
82.83 ± 19.37
|
80.23 ± 17.58
|
|
Minimal effective doses of medication
|
3.89 ± 2.28
|
4.09 ± 2.35
|
4.04. ± 2.54
|
3.36 ± 2.28
|
3.89 ± 2.26
|
4.03 ± 2.43
|
|
Diabetes mellitus (%)
|
14.8
|
15.0
|
14.9
|
12.7
|
12.9
|
12.4
|
|
Controlled hypertension (%)
|
42.27
|
38.88
|
42.62
|
43.44
|
42.90
|
42.62
|
|
Smoking (%)
|
32.40
|
31.30
|
31.42
|
15.39
|
15.46
|
15.24
|
|
Anamnesis of stroke (%)
|
6.19
|
6.28
|
6.79
|
5.41
|
5.25
|
5.38
|
|
Anamnesis of MI (%)
|
10.88
|
10.73
|
10.62
|
5.50
|
5.01
|
5.78
|
|
BB (%)
|
31.83
|
29.50
|
29.93
|
35.10
|
34.13
|
32.80
|
|
ACEI/sartans (%)
|
89.83
|
90.42
|
89.70
|
92.03
|
93.00
|
91.72
|
|
Diuretics (%)
|
39.86
|
37.96
|
40.86
|
40.78
|
40.66
|
41.90
|
|
CCB (%)
|
35.69
|
37.75
|
34.10
|
34.37
|
33.25
|
34.21
|
|
CAH (%)
|
10.55
|
9.56
|
10.94
|
12.78
|
11.83
|
11.57
|
- Values are displayed as mean ± SD
-
ACEI Angiotensin-converting enzyme inhibitors; BMI body mass index (kg/m2); BB beta blockers; CAH central antihypertensives; CCB calcium channel blockers; DBP diastolic blood pressure; SBP systolic blood pressure (mmHg); MI anamnesis of myocardial infarction
- * Significantly different (p < 0.05) than in other cohorts by weight change using ANOVA with Tukey post hoc test for quantitative variables and Chi-square test for qualitative variables
