Table 1 Overview of the examination results regarding the mean, the standard deviation, and the statistical calculations

PGE-2 concentration in synovial fluid (pg/ml)

3399.7 (± 3492.8)

10,871.2 (± 4274.9)

11,098.7 (± 7738.2)

9920.7 (± 5815.4)

*p = 0.018

°p = 0.667

3 wks vs 6 wks

p = 0.022

p = 0.921

New bone area (mm²)

5.09 (± 0.98)

6.45 (± 1.23)

6.55 (± 3.2)

5.7 (± 2.39)

A

*p = 0.028

°p = 0.699

3 wks vs 6 wks

p = 0.302

p = 0.439

New bone area (mm²)

5.63 (± 0.98)

5.55 (± 1.02)

5.59 (± 1.34)

4.75 (± 1.4)

M

*p = 0.897

°p = 0.317

3 wks vs 6 wks

p = 0.699

p = 0.317

New bone area (mm²)

A vs M

p = 0.123

p = 0.028

p = 0.345

p = 0.398

Bone mineral density (mg HA/mm³)

453.92 (± 41.85)

504.23 (± 33.77)

484.78 (± 63.61)

465.04 (± 77.91)

A

*p = 0.020

°p = 0.731

3 wks vs 6 wks

p = 0.302

p = 0.332

Bone mineral density (mg HA/mm³)

231.57 (± 31.81)

222.52 (± 33.31)

216.76 (± 46.18)

216.88 (± 40.25)

M

*p = 0.414

°p = 0.228

3 wks vs 6 wks

p = 0.651

p = 0.475

Bone mineral density (mg HA/mm³)

A vs M

p = 0.012

p = 0.028

p = 0.028

p = 0.018

Failure load (N)

69.33 (± 50.47)

28.2 (± 20.89)

37.4 (± 16.82)

59.57 (± 53.6)

Failure load (N)

*p = 0.171

°p = 0.914

3 wks vs 6 wks

p = 0.240

p = 0.394

Stiffness (N/mm)

9.15 (± 5.64)

5.24 (± 5.47)

6.29 (± 3.79)

10.68 (± 10.21)

Stiffness (N/mm)

*p = 0.352

°p = 0.762

3 wks vs 6 wks

p = 0.522

p = 0.522