Table 1 Preoperative and perioperative results in patients managed routinely (group A, early phase) or following a PPMI reduction protocol (group B, late phase)
Group A (35) | Group B (31) | p-value | |
|---|---|---|---|
Age (years) | 81.4 ± 6.1 | 79.4 ± 4.7 | 0.1 |
Female gender | 57.1% | 58.1% | 0.9 |
Body mass index | 27.3 ± 4.4 | 27.3 ± 4.2 | 0.9 |
LVEF% | 55.6 ± 12.1 | 50.8 ± 16.1 | 0.1 |
A-V block first degree | 8.6% | 9.7% | 0.6 |
Right bundle branch block | 14.3% | 12.9% | 0.5 |
Left bundle branch block | 20.0% | 16.1% | 0.4 |
Logistic Euro-score | 5.1–49.7; 12.6 | 3.1–68.0; 14.2 | 0.2 |
Euro-score II | 1.2–16.4; 3.5 | 2.0–28.0; 3.8 | 0.08 |
STS-score (mortality) | 2.0–9.2; 3.5 | 2.0–16.0; 4.0 | 0.04 |
Annulus (mm) | 24.4 ± 2.0 | 24.0 ± 1.9 | 0.4 |
LVOT (mm) | 24.2 ± 2.1 | 24.0 ± 2.3 | 0.4 |
Bulbus aortae (mm) | 31.0 ± 3.5 | 30.3 ± 2.2 | 0.4 |
Calcification vertical extension (mm)a | 11.1 ± 4.8 | 11.3 ± 3.3 | 0.8 |
Operative time (min) | 46–290; 78 | 40–135; 80 | 0.3 |
Radiation time (mm) | 12–43; 23 | 11–64; 21 | 0.6 |
Valve retrieval | 3% | 9.6% | 0.2 |
Valve full resheating | 8.6% | 19.2% | 0.2 |
Valve post-dilatation | 0 | 0 | |
Prosthesis size (mm) | 24.9 ± 1.6 | 24.9 ± 1.5 | 0.9 |
Prosthesis/annulus | 1.02 ± 0.06 | 1.03 ± 0.05 | 0.4 |
Aortic valve area (cm2) | 1.5 ± 0.3 | 1.5 ± 0.4 | 0.8 |
Mean gradient (mmHg) | 9.0 ± 4.5 | 6.3 ± 2.6 | 0.01 |
Paravalvular leak (0–1–2) | 77.1%–22.9%–0% | 87.9%–12.1%–0% | 0.08 |
In-hospital death | 0 | 9.6% | 0.09 |
Stroke | 0 | 0 | |
AKI | 3% | 3.8% | 0.3 |
Bleeding (major–minor–none) | 8.6%–23%–69% | 0–26.9%–73.1% | 0.3 |
New PPMI | 34.3% | 9.7% | 0.02 |
Early safety (30-days) | 100% | 90.4% | 0.09 |