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Table 1 Clinical features of patients and their donors as well as the outcomes of 24 cases

From: Clinical evaluation of haploidentical hematopoietic combined with human umbilical cord-derived mesenchymal stem cells in severe aplastic anemia

Case Sex/age Donor/age HLA -matched ABO pairs D/R MNC 108/kg CD34+ 106/kg ANC > 2 × 109/L (D) PLT > 20 × 109/L (D) aGVHD grade/cGVHD grade Outcome (M)
1 F/25 Mother/47 3/6 B/AB 9.43 1.9 12 15 –/– Dead 3
2 M/14 Mother/39 3/6 O/B 10.96 12.83 12 13 –/– Dead 3
3 M/5 Mother/30 4/6 AB/B 10.2 2.79 12 13 III/Ext Dead 12
4 M/9 Sister/22 5/6 O/O 10.37 3.24 10 12 IV/Ext Alive 12
5 M/23 Mother/51 4/6 B/B 8.1 2.97 10 14 –/Ext Alive 10
6 F/18 Brother/22 3/6 O/O 10.56 4.546 10 14 II/Lim Alive 13
7 M/16 Father/43 3/6 B/B 8.82 3.25 10 14 III/– Alive 13
8 M/13 Mother/33 3/6 0/A 10.97 3.47 9 10 III/– Alive 11
9 M/22 Father/41 4/6 O/A 10.06 3.79 8 14 IV/– Dead 4
10 F/9 Mother/31 3/6 A/A 9.62 4.71 10 12 –/– Alive 10
11 M/21 Father/45 3/6 A/A 10.83 4.02 11 13 –/– Alive 11
12 M/25 Mother/48 3/6 A/AB 8.05 3.45 13 13 II/– Alive 19
13 F/25 Mother/47 3/6 A/A 12.47 18.65 11 15 III/– Alive 17
14 F/8 Mother/32 3/6 A/A 10.03 5.33 12 15 I/– Alive 16
15 M/16 Father/43 3/6 B/B 13.18 7.96 13 15 –/– Alive 15
16 F/17 Sister/27 3/6 B/B 6.3 3.75 21 25 –/– Alive 20
17 F/13 Mother/46 4/6 O/AB 9.96 10.2 12 12 I/– Alive 27
18 M/17 Father/37 3/6 O/O 9.36 7.52 11 13 I/Lim Alive 41
19 F/24 Sister/21 4/6 A/A 9.66 6.94 11 13 –/– Alive 41
20 M/20 Sister/23 3/6 B/AB 9.28 5.08 16 18 I/Lim Alive 44
21 M/15 Mother/37 4/6 O/O 7.93 3.76 8 10 –/– Dead 3
22 F/13 Sister/18 5/6 B/B 11.2 12.56 10 10 –/– Alive 4
23 M/8 Mother/32 3/6 A/A 8.1 3.94 10 12 –/– Alive 5
24 F/55 Brother/49 3/6 O/B 9.24 4.72 10 11 –/– Alive 12
  1. F female, M male, HLA human leukocyte antigen, D donor, R recipient, MNC mononuclear cells, ANC absolute neutrophil count, PLT platelets, aGVHD acute graft-versus-host disease, cGVHD chronic graft-versus-host disease, Ext extensive, Lim limited, D day, M months