|
Variables
|
Severe aGVHD
|
Extensive cGVHD
|
|---|
|
Incidence (%)
|
r
|
P value
|
Incidence (%)
|
r
|
P value
|
|---|
|
Gender
| |
0.293
|
0.134
| |
0.319
|
0.060
|
|
Male
|
5/14 (35.7%)
| | |
3/14 (21.4%)
| | |
|
Female
|
1/10 (10%)
| | |
0/10
| | |
|
Age, years
| |
0.05
|
0.807
| |
0.033
|
0.872
|
|
≥ 20
|
2/9 (22.2%)
| | |
1/9 (11.1%)
| | |
|
< 20
|
4/15 (26.7%)
| | |
2/15 (13.3%)
| | |
|
Donor-recipient relationship
| |
0.083
|
0.599
| |
0.055
|
0.465
|
|
Mother–child
|
3/12 (25%)
| | |
2/12 (16.7%)
| | |
|
Father–child
|
2/5 (25%)
| | |
0/5
| | |
|
Siblings
|
1/7 (14.3%)
| | |
1/7 (14.3%)
| | |
|
Patient/donor pair
| |
0.225
|
0.566
| |
0.541
|
0.022
|
|
3 HLA loci
|
3/16 (18.8%)
| | |
0/16
| | |
|
2 HLA loci
|
2/6 (33.3%)
| | |
2/6 (33.3%)
| | |
|
1 HLA loci
|
1/2 (50%)
| | |
1/2 (50%)
| | |
|
Severe aGVHD
| | | | |
0.364
|
0.099
|
|
Yes
| | | |
2/6 (33.3%)
| | |
|
No
| | | |
1/18 (5.6%)
| | |
- HSCT hematopoietic stem cell transplantation, aGVHD acute graft-versus-host disease, cGVHD chronic graft-versus-host disease, HLA human leukocyte antigen
