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Table 1 Comparison on demographic and clinical data for NPE and CNSD children patients

From: Correlation analysis on serum inflammatory cytokine level and neurogenic pulmonary edema for children with severe hand–foot–mouth disease

 

NPE group

CNSD group

P value

N

42

47

0.015

Age (months, \( \bar{x} \pm s \))

17.55 ± 5.12

22.94 ± 10.37

0.552

Boy (cases, (%))

23 (54.76)

30 (63.83)

0.257

Body mass (kg, \( \bar{x} \pm s \))

11.86 ± 2.02

12.72 ± 2.71

 

Residence

  

0.267

 City

10 (23.81)

13 (27.66)

 

 Rural area

22 (52.38)

22 (46.81)

 

 Rural–urban fringe zone

10 (23.81)

12 (25.53)

 

Length of stay (days) median (P25 and P75)

8 (6,9)

6 (5,7)

0.000

Maximum body temperature (°C, \( \bar{x} \pm s \))

38.89 ± 0.60

38.73 ± 0.80

0.480

Duration of fever (days) median (P25 and P75)

4 (4,5)

3 (2,4)

0.000

Cardiac rhythm (times/min, \( \bar{x} \pm s \))

227.21 ± 28.23

161.09 ± 23.31

0.000

EV71-positive cases (%)

37 (88.10)

29 (61.70)

0.024

White blood cell count (×109/L, \( \bar{x} \pm s \))

13.75 ± 3.68

12.84 ± 2.78

0.033

CRP (mg/L, \( \bar{x} \pm s \))

15.43 ± 10.31

9.83 ± 6.28

0.898

Blood sugar (mmol/L, \( \bar{x} \pm s \))

7.58 ± 1.83

6.16 ± 1.14

0.003

IVI therapy cases (%)

37 (88.10)

38 (80.85)

0.786

Hormonal therapy cases (%)

40 (95.24)

43 (91.49)

0.901

  1. CNSD, central nervous system disease; NEP, neurogenic pulmonary edema; CPR, C-reactive protein; EV71, human enterovirus 71; IVIG, intravenous immune globulin
  2. at test; b χ2 test; c Mann–Whitney U test