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Table 1 Comparison of index among divided groups according to BMD of femur neck

From: Correlation of serum levels of fibroblast growth factor 23 and Klotho protein levels with bone mineral density in maintenance hemodialysis patients

Item

Normal bone mass (n = 22)

Osteopenia (n = 41)

Osteoporosis (n = 62)

P value

Age (years)

56.091 ± 15.832

59.976 ± 14.828

68.161 ± 12.575a,b

0.001

Male [case (%)]

14 (63.64)

29 (70.73)

30 (48.39)

0.068

Smoking [case (%)]

6 (27.27)

10 (24.39)

18 (29.03)

0.874

Diabetes [case (%)]

6 (27.27)

11 (26.83)

29 (46.77)

0.072

Hypertension [case (%)]

14 (63.64)

29 (70.73)

46 (74.19)

0.641

Hemodialysis duration [month, M (1/4, 3/4)]

64.50 (51.00, 70.25)

59.00 (52.00, 85.00)

68.00 (54.00, 93.25)

0.680

Kt/V

1.752 ± 0.299

1.831 ± 0.489

1.859 ± 0.462

0.628

BMI (kg/m2)

21.448 ± 3.651

21.244 ± 3.695

20.224 ± 2.839

0.178

Hb (g/L)

105.500 ± 11.300

105.390 ± 12.438

104.726 ± 11.857

0.947

Glu [mmol/L, M (1/4, 3/4)]

6.70 (5.69, 7.90)

7.05 (5.71, 8.71)

7.15 (5.83, 10.03)

0.412

Alb (g/L)

40.032 ± 1.845

39.585 ± 3.190

39.076 ± 2.569

0.318

Adjusted Ca (mmol/L)

2.237 ± 0.258

2.314 ± 0.185

2.304 ± 0.193

0.321

P (mmol/L)

1.501 ± 0.450

1.536 ± 0.466

1.666 ± 0.457

0.217

Ca × P (mg2/dL2)

40.397 ± 13.849

44.991 ± 13.702

47.710 ± 14.122

0.107

PTH [ng/L, M (1/4, 3/4)]

225.70 (104.40, 750.68)

290.90 (131.30, 815.70)

432.50 (217.78, 889.63)

0.132

1,25(OH)2VitD3 (ng/mL)

32.486 ± 6.482

33.095 ± 6.080

32.612 ± 6.756

0.914

FGF23 (ng/L)

99.639 ± 22.052

92.646 ± 19.382

102.013 ± 20.085

0.072

Klotho protein (ng/L)

429.883 ± 41.776

410.598 ± 61.056

387.172 ± 54.137a,b

0.005

  1. aP < 0.05 vs Normal bone mass
  2. bP < 0.05 vs Osteopenia