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Table 1 Comparison of index among divided groups according to BMD of femur neck

From: Correlation of serum levels of fibroblast growth factor 23 and Klotho protein levels with bone mineral density in maintenance hemodialysis patients

Item Normal bone mass (n = 22) Osteopenia (n = 41) Osteoporosis (n = 62) P value
Age (years) 56.091 ± 15.832 59.976 ± 14.828 68.161 ± 12.575a,b 0.001
Male [case (%)] 14 (63.64) 29 (70.73) 30 (48.39) 0.068
Smoking [case (%)] 6 (27.27) 10 (24.39) 18 (29.03) 0.874
Diabetes [case (%)] 6 (27.27) 11 (26.83) 29 (46.77) 0.072
Hypertension [case (%)] 14 (63.64) 29 (70.73) 46 (74.19) 0.641
Hemodialysis duration [month, M (1/4, 3/4)] 64.50 (51.00, 70.25) 59.00 (52.00, 85.00) 68.00 (54.00, 93.25) 0.680
Kt/V 1.752 ± 0.299 1.831 ± 0.489 1.859 ± 0.462 0.628
BMI (kg/m2) 21.448 ± 3.651 21.244 ± 3.695 20.224 ± 2.839 0.178
Hb (g/L) 105.500 ± 11.300 105.390 ± 12.438 104.726 ± 11.857 0.947
Glu [mmol/L, M (1/4, 3/4)] 6.70 (5.69, 7.90) 7.05 (5.71, 8.71) 7.15 (5.83, 10.03) 0.412
Alb (g/L) 40.032 ± 1.845 39.585 ± 3.190 39.076 ± 2.569 0.318
Adjusted Ca (mmol/L) 2.237 ± 0.258 2.314 ± 0.185 2.304 ± 0.193 0.321
P (mmol/L) 1.501 ± 0.450 1.536 ± 0.466 1.666 ± 0.457 0.217
Ca × P (mg2/dL2) 40.397 ± 13.849 44.991 ± 13.702 47.710 ± 14.122 0.107
PTH [ng/L, M (1/4, 3/4)] 225.70 (104.40, 750.68) 290.90 (131.30, 815.70) 432.50 (217.78, 889.63) 0.132
1,25(OH)2VitD3 (ng/mL) 32.486 ± 6.482 33.095 ± 6.080 32.612 ± 6.756 0.914
FGF23 (ng/L) 99.639 ± 22.052 92.646 ± 19.382 102.013 ± 20.085 0.072
Klotho protein (ng/L) 429.883 ± 41.776 410.598 ± 61.056 387.172 ± 54.137a,b 0.005
  1. aP < 0.05 vs Normal bone mass
  2. bP < 0.05 vs Osteopenia