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Table 1 Baseline clinical characteristics of the patients

From: Coenzyme Q10 combined with trimetazidine in the prevention of contrast-induced nephropathy in patients with coronary heart disease complicated with renal dysfunction undergoing elective cardiac catheterization: a randomized control study and in vivo study

Variables

CoQ10 + TMZ group (n = 75)

Control group (n = 75)

p value

Age (years)

61.75 ± 9.15

63.52 ± 7.88

0.205

Female, n (%)

34 (45.33)

33 (44.00)

0.870

BMI (kg/m2)

26.30 ± 4.06

25.43 ± 2.85

0.131

Hypertension, n (%)

32 (42.67)

35 (46.67)

0.622

Diabetes mellitus, n (%)

31 (41.33)

34 (45.33)

0.621

Hyperlipidemia, n (%)

29 (38.67)

26 (34.67)

0.611

Smoking, n (%)

39 (52.00)

41 (54.67)

0.743

LVEF (%)

56.18 ± 6.53

54.62 ± 5.68

0.121

AMI, n (%)

13 (17.33)

10 (13.33)

0.479

Previous myocardial infarction n (%)

11 (14.67)

8 (20.67)

0.461

Laboratory results

 Hemoglobin (g/L)

125.01 ± 9.28

126.25 ± 9.72

0.426

 Glycosylated hemoglobin (%)

6.08 ± 0.88

6.26 ± 1.00

0.229

 Low-density lipoprotein cholesterol (mg/dL)

118.79 ± 18.45

117.75 ± 21.39

0.750

Medications, n (%)

 β-blocker

52 (69.33)

49 (65.33)

0.601

 ACEI/ARB

42 (56.00)

38 (50.67)

0.513

 Statins

67 (89.33)

71 (94.67)

0.229

 Diuretics

6 (8.00)

8 (10.67)

0.575

 Nitrate

40 (53.33)

46 (61.33)

0.322

 Calcium-channel blocker

32 (42.67)

38 (50.67)

0.326

 Proton pump inhibitors

20 (26.67)

16 (21.33)

0.444

 PCI, n (%)

39 (52.00)

36 (48.00)

0.624

 Use of bivalirudin, n (%)

26 (34.67)

21 (28.00)

0.379

 Use of GPI, n (%)

15 (20.00)

16 (21.33)

0.840

 Volume of CM (mL)

136.40 ± 68.57

130.13 ± 63.79

0.563

 CM ≥ 160 mL, n (%)

35 (46.67)

30 (40.00)

0.410

 Hydration volume (mL)

1754.40 ± 358.41

1716.32 ± 238.30

0.445

  1. BMI Body mass index, AMI acute myocardial infarction, LVEF left ventricular ejection fraction, ACEI angiotensin-converting enzyme inhibitors, ARB angiotensin receptor blockers, PCI percutaneous coronary intervention, GPI platelet glycoprotein IIb/IIIa inhibitors, CM contrast medium