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Table 4 Blood urea nitrogen and serum creatinine at the post-treatment with the CoQ10 and TMZ in CM-induced AKI model

From: Coenzyme Q10 combined with trimetazidine in the prevention of contrast-induced nephropathy in patients with coronary heart disease complicated with renal dysfunction undergoing elective cardiac catheterization: a randomized control study and in vivo study

Groups

sham

CM

CM + CoQ10 and TMZ (10 mg/kg)

CM + CoQ10 and TMZ (20 mg/kg)

N

8

8

8

8

BUN (mg/dL)

26.3 ± 0.82

57.1 ± 5.67#

44.3 ± 4.38*

33.1 ± 3.21**

Scr (mg/dL)

0.38 ± 0.07

0.63 ± 0.06#

0.51 ± 0.09*

0.43 ± 0.05*

  1. # p < 0.05, compared with sham control; * p < 0.05, ** p < 0.01, compared with CM model group