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Table 3 Median survival by TNM categories (n = 98) using the sixth and seventh editions of the TNM classification

From: Comparison of the sixth and the seventh editions of the UICC classification for intrahepatic cholangiocarcinoma

UICC N (%) Median survival in months (range) Log-rank test (p value) Cox regression analysis (p value) 1-year survival (%) 3-year survival (%) 5-year survival (%)
Patients edition    0.02 0.27    
 T1 52 (53.1%) 47.30 (0.30–149.29)    86.5 44.2 19.2
 T2 15 (15.3%) 15.60 (0.23–97.05)    60.0 20.0 13.3
 T3 25 (25.5%) 24.80 (0.16–150.11)    64.0 24.0 12.0
 T4 6 (6.1%) 26.95 (3.84–43.17)    66.7 33.3 0.0
7th edition    0.004 0.09    
 T1 48 (49.0%) 50.40 (0.30–149.29)    85.4 47.9 20.8
 T2 38 (38.8%) 19.88 (0.16–150.11)    63.2 23.7 13.2
 T3 10 (10.2%) 21.62 (2.69–43.17)    70.0 20.0 0.0
 T4 2 (2.0%) 19.86 (19.38–20.34)    100.0 0.0 0.0
6th edition    0.05 0.74    
 N0 72 (73.5%) 41.26 (0.16–149.29)    77.8 36.1 18.1
 N1 26 (26.5%) 22.70 (2.69–150.11)    69.2 30.8 7.7
7th edition    0.05 0.74    
 N0 72 (73.5%) 41.26 (0.16–149.29)    77.8 36.1 18.1
 N1 26 (26.5%) 22.70 (2.69–150.11)    69.2 30.8 7.7
6th edition    0.21 N/a    
 M0 96 (98.0%) 27.79 (0.16–150.11)    76.0 35.4 15.6
 M1 2 (2.0%) 15.29 (2.69–27.89)    50.0 0.0 0.0
7th edition    0.45 N/a    
 M0 91 (92.9%) 27.79 (0.16–150.11)    76.9 34.1 16.5
 M1 7 (7.1%) 27.89 (2.69–54.97)    57.1 42.9 0.0
  1. Survival was calculated using the Kaplan–Meier method and compared using the log-rank test. Cox proportional hazards regression analysis was performed to evaluate the prognostic value of the TNM categories according to the sixth and seventh editions