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Table 3 Median survival by TNM categories (n = 98) using the sixth and seventh editions of the TNM classification

From: Comparison of the sixth and the seventh editions of the UICC classification for intrahepatic cholangiocarcinoma

UICC

N (%)

Median survival in months (range)

Log-rank test (p value)

Cox regression analysis (p value)

1-year survival (%)

3-year survival (%)

5-year survival (%)

Patients edition

  

0.02

0.27

   

 T1

52 (53.1%)

47.30 (0.30–149.29)

  

86.5

44.2

19.2

 T2

15 (15.3%)

15.60 (0.23–97.05)

  

60.0

20.0

13.3

 T3

25 (25.5%)

24.80 (0.16–150.11)

  

64.0

24.0

12.0

 T4

6 (6.1%)

26.95 (3.84–43.17)

  

66.7

33.3

0.0

7th edition

  

0.004

0.09

   

 T1

48 (49.0%)

50.40 (0.30–149.29)

  

85.4

47.9

20.8

 T2

38 (38.8%)

19.88 (0.16–150.11)

  

63.2

23.7

13.2

 T3

10 (10.2%)

21.62 (2.69–43.17)

  

70.0

20.0

0.0

 T4

2 (2.0%)

19.86 (19.38–20.34)

  

100.0

0.0

0.0

6th edition

  

0.05

0.74

   

 N0

72 (73.5%)

41.26 (0.16–149.29)

  

77.8

36.1

18.1

 N1

26 (26.5%)

22.70 (2.69–150.11)

  

69.2

30.8

7.7

7th edition

  

0.05

0.74

   

 N0

72 (73.5%)

41.26 (0.16–149.29)

  

77.8

36.1

18.1

 N1

26 (26.5%)

22.70 (2.69–150.11)

  

69.2

30.8

7.7

6th edition

  

0.21

N/a

   

 M0

96 (98.0%)

27.79 (0.16–150.11)

  

76.0

35.4

15.6

 M1

2 (2.0%)

15.29 (2.69–27.89)

  

50.0

0.0

0.0

7th edition

  

0.45

N/a

   

 M0

91 (92.9%)

27.79 (0.16–150.11)

  

76.9

34.1

16.5

 M1

7 (7.1%)

27.89 (2.69–54.97)

  

57.1

42.9

0.0

  1. Survival was calculated using the Kaplan–Meier method and compared using the log-rank test. Cox proportional hazards regression analysis was performed to evaluate the prognostic value of the TNM categories according to the sixth and seventh editions