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Table 2 Studies characteristics of each article included in the meta-analysis and distribution of genotype frequency of GSTM1 among controls and cirrhotic patients

From: The influence of polymorphic GSTM1 gene on the increased susceptibility of non-viral hepatic cirrhosis: evidence from observational studies

First author Year Country Cirrhosis type Sample size (case/control) Genotyping method Control source Matched factors Score Case group Control group
GSTM1 active, N (%) GSTM1 null, N (%) GSTM1 active, N (%) GSTM1 null, N (%)
Khan [18] 2010 India Alcoholic HC 140/175 Multiple PCR HB Age, ethnicity, region 8 98 (56.0%) 77 (44.0%) 96 (68.5%) 44 (31.5%)
Khan [19] 2009 India Alcoholic HC 160/100 Multiple PCR HB Region 8 92 (57.0%) 68 (43.0%) 70 (70.0%) 30 (30.0%)
Burim [21] 2004 Brazil Alcoholic HC 65/221 Multiple PCR HB Age, gender, ethnicity, drink habits 9 35 (53.8%) 30 (46.2%) 120 (54.3%) 101 (45.8%)
Frenzer [20] 1999 Australia Alcoholic HC 57/57 Multiple PCR HB Age, ethnicity, drink habits 8 3 (5.3%) 54 (94.7%) 10 (17.5%) 47 (82.5%)
Rodrigo [22] 2005 Spain Alcoholic HC 120/200 PCR–RFLP PB Sex, region 6 51 (42.5%) 69 (57.5%) 90 (45.0%) 110 (55.0%)
Davies [23] 1993 Birmingham Primary biliary HC 44/68 Horizontal starch gel electrophoresis HB None 5 27 (61.0%) 17 (39.0%) 37 (54.4%) 31 (45.6%)
  1. HB hospital based, PB population based