Fig. 3

Hypoxia-induced vasomotion of arterial segments from eNOS^−/−- and TASK1^−/−-mice. a Percentage of dilating arterial segments of eNOS^−/−-mice in Tyrode’s solution containing Ca²⁺ (Y-axis) as function of the oxygen concentration (X-axis). The black line represents the experiments with eNOS^−/−-mice and the grey line represents the controls from wt-mice (n = number of arteries responding with vasodilatation from a total number of eight). b Percentage change in luminal diameter from eNOS^−/−-mice is represented in relation to the maximal dilatation induced by 0.1 mM nitroprusside sodium (n = arterial segments responding with vasodilation from a total number of eight). c Percentage change in luminal diameter from TASK1^−/−-mice in relation to the maximal reaction (dilatation or contraction). Negative algebraic sign on the Y-axis: constriction of the arterial segment; *p < 0.05; **p < 0.01 (n = number of independent experiments; Student t test for paired samples)