From: Vasomotion of mice mesenteric arteries during low oxygen levels
Oxygen concentration (%) | ||||
---|---|---|---|---|
14.4 n = 24 | 12.2 n = 26 | 2.7 | 0 | |
Percentage of the initial diameter | ||||
Overall | 0.58 ± 0.59 (n = 10) | 0.77 ± 0.57 (n = 10) | 0.92 ± 0.64 (n = 10) | 0.43 ± 0.28 (n = 5) |
Constriction | − 0.79 ± 0.05 (n = 5) | − 0.765 ± 0.14 (n = 4) | − 1.213 ± 0.28 (n = 3) | − 0.6 (n = 1) |
Dilation | 1.96 ± 0.55 (n = 5) | 1.8 ± 0.52 (n = 6) | 1.83 ± 0.52 (n = 7) | 0.68 ± 0.13 (n = 4) |
Percentage of maximal dilatation and constriction | ||||
Overall | 23.2 ± 14.62 (n = 10) | 26.92 ± 14.35 (n = 10) | 31.94 ± 15.32 (n = 10) | 14 ± 5.96 (n = 5) |
Constriction | − 8.21 ± 0.56 (n = 5) | − 7.92 ± 4.42 (n = 5) | − 12.54 ± 2.92 (n = 5) | − 6.21 (n = 1) |
Dilation | 54.6 ± 15.31 (n = 5) | 50.14 ± 14.41 (n = 6) | 51.01 ± 14.42 (n = 7) | 19.05 ± 3.61 (n = 4) |
Percentage of the initial diameter in Ca2+-free Tyrode’s solution | ||||
Overall | 0.36 ± 0.39 (n = 8) | 1.07 ± 0.38 (n = 8) | 1.52 ± 0.43 (n = 8) | − |
Constriction | − 1.14 ± 0.4 (n = 2) | − 0.39 (n = 1) | – | − |
Dilation | 0.85 ± 0.19 (n = 6) | 1.49 ± 0.3 (n = 6) | 1.53 ± 0.42 (n = 7) | − |
Percentage of maximal dilatation and constriction in Ca2+-free Tyrode’s solution | ||||
Overall | 14.93 ± 7.5 (n = 8) | 38.58 ± 10.03 (n = 8) | 37.36 ± 12.06 (n = 8) | – |
Constriction | − 11.8 ± 4.14 (n = 2) | − 4.01 (n = 1) | – | – |
Dilation | 23.82 ± 5.29 (n = 6) | 41.51 ± 8.35 (n = 6) | 42.7 ± 11.68 (n = 7) | – |
Percentage of the initial diameter in Tyrode’s solution containing NiCl2 | ||||
Overall | − 1.31 ± 0.49 (n = 6) | − 1.42 ± 0.48 (n = 6) | − 1.54 ± 0.44 (n = 6) | – |
Percentage of maximal constriction in Tyrode’s solution containing NiCl2 | ||||
Overall | − 13.6 ± 5.03 (n = 6) | − 14.7 ± 4.93 (n = 6) | − 15.93 ± 4.52 (n = 6) | - |
Percentage of the initial diameter in eNOS− /−-mice | ||||
Overall | − 0.42 ± 0.31 (n = 8) | − 0.33 ± 0.6 (n = 8) | − 0.21 ± 0.68 (n = 8) | – |
Constriction | − 1.37 ± 0.22 (n = 3) | − 2.05 ± 0.52 (n = 3) | − 2.32 ± 0.46 (n = 3) | – |
Dilation | 0.4 ± 0.1 (n = 2) | 0.88 ± 0.16 (n = 4) | 1.05 ± 0.17 (n = 5) | – |
Percentage of maximal dilatation and constriction in eNOS−/−-mice | ||||
Overall | − 2.56 ± 4.1 (n = 8) | 3.43 ± 9.21 (n = 8) | 9.38 ± 10.73 (n = 8) | – |
Constriction | − 10.64 ± 2.3 (n = 3) | − 23.64 ± 4 (n = 3) | − 24 ± 4.73 (n = 3) | – |
Dilation | 11.05 ± 2.3 (n = 2) | 24.59 ± 4.58 (n = 4) | 29.4 ± 4.85 (n = 5) | – |
Percentage of the initial diameter in TASK1−/−-mice | ||||
Overall | 0.46 ± 0.38 (n = 4) | 0.32 ± 0.9 (n = 4) | 0.15 ± 1.03 (n = 4) | – |
Constriction | − 0.31 (n = 1) | − 2.19 (n = 1) | − 2.5 (n = 1) | – |
Dilation | 1.07 ± 0.24 (n = 2) | 1.16 ± 0.42 (n = 3) | 1.55 ± 0.65 (n = 2) | – |
Percentage of maximal dilatation and constriction in TASK1−/−-mice | ||||
Overall | 14.08 ± 9.89 (n = 4) | 18.56 ± 16.67 (n = 4) | 15.16 ± 19 (n = 4) | – |
Constriction | − 3.23 (n = 1) | − 22.6 (n = 1) | − 25.86 (n = 1) | – |
Dilation | 29.78 ± 6.75 (n = 2) | 32.3 ± 11.57 (n = 3) | 43.24 ± 18.08 (n = 2) | – |