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Fig. 2 | European Journal of Medical Research

Fig. 2

From: Ingenol mebutate induces a tumor cell-directed inflammatory response and antimicrobial peptides thereby promoting rapid tumor destruction and wound healing

Fig. 2

Ingenol mebutate (IM) induces a mixed inflammatory infiltrate. Histopathology of an actinic keratosis of the scalp on day 4 after a treatment with ingenol mebutate (IM)-0.015%-gel for 3 consecutive days. IM recruits a dense neutrophil-rich infiltrate (a) (hematoxylin and eosin stain). Myeloperoxidase staining reveals also abundant neutrophils in the Stratum corneum, forming microabscesses (b). CD3 stains for chemoattracted T cells (c), CD68 for histiocytes and neutrophils (d)

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