Fig. 2

Nuclear magnetic resonance images of the knee joint before and after treatment with BIOF2. Axial views at the height of the patella (a, b) and the femoral condyles (c, d) and coronal views (e, f), before and after 12 months of treatment, respectively. The arrows indicate the zones in which treatment generated a beneficial change, with respect to cartilage thickness or continuity. 1: cartilage, 2: femur, 3: patella 4: femoral condyle, 5: muscle, 6: tibia