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Table 1 Basic characteristics of the participants

From: The effect of statin treatment on circulating coenzyme Q10 concentrations: an updated meta-analysis of randomized controlled trials

Study

Duration

Inclusion criteria

Participants (T/C)

Age (years)

Male (%)

Outcome

T

C

T

C

Jula 2015

12 weeks

Dyslipidemia patients

120 (60/60)

48.4 ± 6.2

48.0 ± 6.2

100

100

Serum CoQ 10 concentrations

Oranje 2001

3 months

Type 2 diabetes patients

19 (9/10)

64 ± 8

63 ± 8

100

70

Plasma CoQ 10 concentrations

Päivä 2005

8 weeks

Dyslipidemia patients

48 (32/16)

31–69

31–69

N

N

Plasma CoQ 10 concentrations

Strey 2005

6 weeks

Heart failure (NYHA II or III) with LVEF < 40%

48 (24/24)

N

N

N

N

Plasma CoQ 10 concentrations

Mortensen 1997

6 weeks

Dyslipidemia patients

45 (23/22)

52.9 (32,69)

54.8 (42,67)

60.9

40.9

Serum CoQ 10 concentrations

Morrison 2017

24 weeks

Patients with HIV

147 (71/75)

45 (41,51)

47 (39,53)

81

76

Plasma CoQ 10 concentrations

McMurray 2010

3 months

Heart failure (NYHA II or III) with LVEF < 40%

1103 (551/552)

N

N

N

N

Serum CoQ 10 concentrations

Ghirlanda 1993

3 months

Dyslipidemia patients

30 (20/10)

47 ± 8; 49 ± 10

47 ± 8

60; 50

70

Plasma CoQ 10 concentrations

Chitose 2014

6 months

STEMI patients

75 (38/37)

64.1 ± 11.8

65.8 ± 12.4

73.7

75.7

Plasma CoQ 10 concentrations

Berthold 2006

14 days

Healthy subjects

48 (24/24)

31.9 ± 8.8

28.6 ± 6.6

N

N

Plasma CoQ 10 concentrations

Barry 2001

4 weeks

Healthy subjects

24 (12/12)

26 ± 5

26 ± 5

41.7

41.7

Plasma CoQ 10 concentrations

Ashton et al. 2011

26 weeks

Heart failure (NYHA II or III) with LVEF < 40%

69 (32/37)

N

N

N

N

Plasma CoQ 10 concentrations

  1. NYHA New York Heart Association, LVEF left ventricular ejection fraction, HIV human immunodeficiency virus, STEMI st segment elevation myocardial infarction, CAD coronary artery disease, CK creatine kinase, CoQ10 coenzyme Q 10, T treatment group, C control group, N not mentioned