Fig. 5

a Network of DE-miRs and their enriched functions. The enriched metabolic functions are labeled. b DE-miR modulatory pattern of enriched metabolic functions. The enriched glucose and lipid metabolism functions regulated by DE-miRs in which “insulin receptor signaling pathway”, “response to glucose stimulus”, “cellular response to insulin stimulus”, “positive regulation of insulin secretion” and “negative regulation of insulin secretion” were targeted by the most miRNAs, suggesting important roles in DA regulation. rno-miR-329-3p, 133a-5p, 325-5p, 133a-3p, and 133b-3p were predicted to modulate the majority of these metabolic functions