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Table 1 Sample description for assessed MitraClip (MC group; N = 40)

From: Effects of MitraClip on cognitive and psychological function in heart failure patients: the sicker the better

 

Pre (t0)

Post (t1)

COGBAT norm percentile (≥ 50 = healthy)

 Planning ability (median; IQR)

30 (11.25 to 42.50)

65 (35 to 80)

 Figural memory (median; IQR)

22.5 (0 to 50)

45 (16.25 to 75)

Patient characteristics and biomarkers

 Age (years; median)

73

–

 Sex (female)

19/40 (47.5%)

–

 MWT-B intelligence quotient (IQ)

110.83 ± 16.3

–

 STS-score (%)

5.16 (5.24)

–

 Psychopharmacological medication (n)

6 (15%)

–

 Ejection fraction (%)

35 ± 15

35 ± 16

 6 min walk distance test (m)

366 ± 7

415 ± 115

 NT-ProBNP (ng/L) (median)

3880

3627

 hsTnT (pg/mL)

36 ± 33

46 ± 80

Pathogenesis and comorbidity

 ICMP (%)

21/40 (52.5%)

–

 DCMP (%)

19/40 (47.5%)

–

 Implantable cardioverter defibrillator (%)

15/40 (37.5%)

–

 Prior cardiothoracic surgery (%)

9/40 (22.5%)

–

 Atrial fibrillation (%)

20/40 (50%)

–

 Prior stroke (%)

4/40 (10%)

–

 Increased retention values (> 1.3 mg/dL) (%)

11/40 (27.5%)

–

 Severe sleep apnea syndrome (%)

4/40 (10%)

–

 Diabetes mellitus (%)

6/40 (15%)

–

 Pulmonary disease

8/40 (20%)

–

 Cancer (%)

1/40 (2.5%)

–

Functional Mitral valve regurgitation (FMR)

 FMR ≤ I°

0

14/40 (35%)

 FMR ≤ II°

0

23/40 (57.5%)

 FMR > II°–< III°

4/40 (10%)

3/40 (7.5%)

 FMR III°

11/40 (27.5%)

0

 FMR IV°

23/40 (57.5%)

0

NYHA functional classification

 NYHA I

0

1/40 (2.5%)

 NYHA II

3/40 (7.5%)

24/40 (60%)

 NYHA III

32/40 (80%)

15/40 (37.5%)

 NYHA IV

5/40 (12.5%)

0

  1. MWT-B multiple selection vocabulary test, STS-score risk score of the Society of Thoracic Surgeons to predict operative mortality of adult cardiac surgery, NT-ProBNP N-terminal pro-brain natriuretic peptide, hsTnT high-sensitive Troponin T, ICMP ischemic cardiomyopathy, DCMP dilated cardiomyopathy, NYHA New York Heart Association, SD standard deviation, IQR interquartile range