Fig. 1
From: Short exposure to tranexamic acid does not affect, in vitro, the viability of human chondrocytes
Tranexamic acid effects on chondrocytes viability. Cells were treated with W-TXA or M-TXA for 10 min and then extensively washed; effects on cell viability were observed soon after treatment—10′/0 h (a) or after 24 h—10′/24 h (b) or 48 h—10′/48 h (c) culture in complete medium. Cells were also incubated with W-TXA or M-TXA for 24 h—24 h (d) or 48 h—48 h (e). Graphs also report viability tests conducted using the same volumes of water (WFI) used in the experiments with W-TXA. Data originated from eight cell cultures, all analyzed in triplicate, and are expressed as % of viability (mean ± SD); in all graphs, the value 100% was conventionally assigned to the viability of untreated cells. The horizontal bars reported on the graphs highlight the significant differences between treatments for each single moment and the asterisks reported on each single bar represent a statistically significant difference of treated cells compared to untreated ones (*p ≤ 0.05 for Tukey’s test)