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Table 1 Percentage of viability for each treatment at all concentrations and moments

From: Short exposure to tranexamic acid does not affect, in vitro, the viability of human chondrocytes

  20 mg/ml 50 mg/ml 70 mg/ml 100 mg/ml
10′/0 h
 Untreated % viability 100 ± 0.00 100 ± 0.00 100 ± 0.00 100 ± 0.00
 WFI % viability 77.75 ± 20.42 74.10 ± 25.56 55.45 ± 25.03 − 11.95 ± 10.92
 W-TXA % viability 91.77 ± 16.76 82.56 ± 12.92 72.21 ± 22.90 20.04 ± 24.36
 M-TXA % viability 92.58 ± 21.31 85.34 ± 23.30 80.66 ± 17.37 80.62 ± 19.54
10′/24 h
 Untreated % viability 100 ± 0.00 100 ± 0.00 100 ± 0.00 100 ± 0.00
 WFI % viability 77.46 ± 35.21 70.12 ± 36.97 57.67 ± 38.81 − 4.14 ± 10.54
 W-TXA % viability 106.48 ± 46.19 95.36 ± 37.60 81.53 ± 33.80 22.88 ± 16.75
 M-TXA % viability 92.45 ± 25.20 86.79 ± 16.73 89.49 ± 15.91 94.38 ± 15.99
10′/48 h
 Untreated % viability 100 ± 0.00 100 ± 0.00 100 ± 0.00 100 ± 0.00
 WFI % viability 78.78 ± 28.05 74.40 ± 26.51 59.43 ± 28.64 − 6.32 ± 6.79
 W-TXA % viability 94.02 ± 30.07 87.85 ± 30.19 74.73 ± 28.23 32.51 ± 23.24
 M-TXA % viability 94.45 ± 34.62 88.82 ± 25.44 93.74 ± 21.35 84.15 ± 13.19
24 h
 Untreated % viability 100 ± 0.00 100 ± 0.00 100 ± 0.00 100 ± 0.00
 WFI % viability 116.66 ± 24.37 92.40 ± 26.77 50.93 ± 20.52 11.06 ± 6.23
 W-TXA % viability 99.33 ± 24.38 60.97 ± 12.99 48.93 ± 14.46 5.99 ± 12.91
 M-TXA % viability 93.13 ± 14.37 63.38 ± 15.14 47.25 ± 21.51 24.34 ± 29.53
48 h
 Untreated % viability 100 ± 0.00 100 ± 0.00 100 ± 0.00 100 ± 0.00
 WFI % viability 121.51 ± 37.41 87.10 ± 40.25 38.76 ± 20.37 9.95 ± 7.51
 W-TXA % viability 85.22 ± 25.67 41.16 ± 25.81 29.35 ± 30.97 2.38 ± 11.48
 M-TXA % viability 75.83 ± 17.39 38.07 ± 20.36 29.29 ± 29.23 17.41 ± 33.14
  1. Average values of OD for each type of treatment and each concentration are expressed as percentage compared to the control experiment OD values (assumed as 100%). Untreated: control experiment; WFI: cells treated with water for injections; W-TXA: cells treated with water-dissolved tranexamic acid; M-TXA: cells treated with medium-dissolved tranexamic acid