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Fig. 2 | European Journal of Medical Research

Fig. 2

From: Dok-3 deficient mice display different immune clustering and Tim-3 expression

Fig. 2

NK cells and DC cells proportion and the Tim-3 expression on these cells in two group mice. Spleen immune cells were isolated from 129 mice (n = 6) and Dok-3−/− mice (n = 6). a Flow cytometry (FCM) analysis of Tim-3 expression on NK cells marked by CD3NK1.1+ (left), and the statistical graph was shown (right), NK cells (129, 4.20 ± 1.335; Dok-3−/−, 3.22 ± 0.577) and Tim-3 expression (129, 30.97 ± 2.089; Dok-3−/−, 47.94 ± 2.871). b Flow cytometry (FCM) analysis of Tim-3 expression on DC cells marked by CD3CD11c+ (left), and the statistical graph was shown (right), DC cells (129, 5.60 ± 0.674; Dok-3−/−, 8.17 ± 0.857) and Tim-3 expression (129, 38.71 ± 1.228; Dok-3−/−, 49.95 ± 3.191). Both the NK cells and DC cells’ gated strategy are shown in Additional file 1: Figure S1. *p < 0.05, **p < 0.01, ***p < 0.001

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