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Table 3 Multivariate analyses for DSS when patients were stratified by age

From: Clinical characteristics associated with primary cardiac angiosarcoma outcomes: a surveillance, epidemiology and end result analysis

Factor Category Multivariable analysis
Age < 45 Age ≥ 45
HR 95% CI P value HR 95% CI P value
Race White    0.963    0.006
Black 1.029 0.479–2.213 0.941 3.141 1.419–6.953 0.005
Other 1.139 0.452–2.870 0.783 0.635 0.283–1.427 0.272
Histological grade I    0.952    
II 0.000   0.838    0179
III 1.602 0.116–22.162 0.725 0.158 0.014–1.742 0.132
IV 1.478 0.095–22.982 0.780 0.076 0.007–0.892 0.040
Unknown 1.165 0.094–14.448 0.906 0.182 0.019–1.704 0.135
Summary stage Localized    0.105    0.024
Regional 0.649 0.279–1.509 0.315 0.517 0.173–1.542 0.236
Distant 1.795 0.796–4.048 0.158 1.435 0.467–4.412 0.529
Unstaged 5.158 0.570–46.644 0.144 0.097 0.010–0.965 0.047
TNM stage I       0.715
II    0.372 9.084 0.368–224.343 0.177
III 0.191 0.023–1.621 0.129 3.737 0.082–170.500 0.499
IV 0.353 0.010–12.959 0.571 7.275 0.173–306.609 0.299
Unknown 0.183 0.024–1.396 0.101 3.437 0.189–62.429 0.404
Tumour size < 3 cm    0.199    0.179
3 cm–5 cm 3.704 0.504–27.233 0.198 2.694 0.493–14.711 0.252
> 5 cm 6.424 0.760–54.292 0.088 5.023 1.026–24.598 0.046
Unknown 7.984 0.941–67.734 0.057 3.820 0.768–19.000 0.101
LN metastases No    0.325    0.498
Yes 4.595 0.619–34.081 0.136 0.550 0.162–1.871 0.339
Unknown 0.000 0.000–2.237E+49 0.877 0.525 0.146–1.888 0.324
Distant metastases No    0.720    0.237
Yes 0.311 0.017–5.577 0.428 0.160 0.016–1.609 0.120
Unknown 32,140.430 0.000–1.281E+58 0.869 1.779 0.372–8.510 0.471
Radiation Yes/no, unknown 1.378 0.692–2.744 0.362 2.205 1.167–4.166 0.015
Surgery Yes/no, unknown 0.947 0.490–1.831 0.429 2.212 1.084–4.516 0.029