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Table 2 Hemodynamic, blood gas, and metabolic parameters during different RRs after achieving adequate intravascular volume

From: Effects of respiratory rate on venous-to-arterial CO2 tension difference in septic shock patients undergoing volume mechanical ventilation

Parameters

Level 1 (RR = 10)

Level 2 (RR = 12)

Level 3 (RR = 14)

Level 4 (RR = 16)

HR, beats/minute

95 ± 19

98 ± 17

97 ± 17

97 ± 15

MAP, mmHg

84 ± 9.5

84 ± 10.9

83 ± 9.8

86.9 ± 11.7

pH

7.35 ± 0.078

7.38 ± 0.092*

7.42 ± 0.059**

7.43 ± 0.078**

PaCO2, mmHg

44.9 ± 7.60

41.6 ± 6.92**

37.2 ± 6.42**

33.5 ± 6.80**

PaO2, mmHg

114.1 ± 24.96

125.0 ± 24.67*

137.6 ± 26.86**

144.3 ± 27.57**

SaO2,  %

98.9 ± 1.15

99.1 ± 0.91

99.2 ± 0.74

99.1 ± 0.90

Lactate, mmol/L

1.78 ± 0.95

1.89 ± 1.29

1.98 ± 0.72

2.15 ± 2.06

BE

0.59 ± 9.48

0.42 ± 6.51

0.70 ± 4.59

0.84 ± 4.40

K+, mmol/L

4.3 ± 0.9

4.3 ± 0.7

4.2 ± 0.7

4.4 ± 0.6

HCO3, mmol/L

28.58 ± 5.22

26.76 ± 4.56*

24.23 ± 4.20*

22.44 ± 4.99*

ctCO2, mmol/L

56.32 ± 21.9

52.62 ± 19.7*

48.33 ± 19.5**

45.21 ± 19.6**

PcvCO2, mmHg

50.66 ± 8.09

48.61 ± 7.21**

45.35 ± 6.99**

41.43 ± 12.50**

ScvO2,  %

73.1 ± 7.7

75.3 ± 7.0

77.1 ± 8.3**

75.2 ± 8.7*

gapCO2, mmHg

5.76 ± 2.02

7.19 ± 1.93*

8.16 ± 1.81**

9.85 ± 1.92**

  1. Data are presented as mean ± SD or absolute values (%)
  2. MAP, mean arterial pressure; PaCO2, partial pressure of carbon dioxide in artery; PcvCO2, central venous carbon dioxide pressure; gapCO2, central venous-to-arterial carbon dioxide difference; ScvO2, central venous oxygen saturation
  3. *P < 0.05 compared with RR of 10 breaths/min, **P < 0.01 compared with RR of 10 breaths/min. Multiple comparisons were used to adjust for the Bonferroni method