Fig. 3
From: Mechanism of HMGB1–RAGE in Kawasaki disease with coronary artery injury
Relative expression levels of HMGB1/RAGE/NF-κB mRNA detected by RT-qPCR. The HMGB1/RAGE/NF-κB mRNA levels were highly expressed in group S than in group N (a). The expression levels of HMGB1/RAGE/NF-κB proteins in coronary artery of rabbit model with KD detected by western blot analysis. The levels in group S are higher compared with group N (b). The expression levels of HMGB1/RAGE/NF-κB proteins in the serum of rabbit model with KD detected by ELISA, those have high expression in both group S and group R compared with group N (c). * show that P<0.05 compared with “group N”. N normal group, S severe group, R recovery group