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Fig. 2 | European Journal of Medical Research

Fig. 2

From: Limb ischemic preconditioning ameliorates renal microcirculation through activation of PI3K/Akt/eNOS signaling pathway after acute kidney injury

Fig. 2

Inhibition of PI3K abolished the renoprotective effects of LIPC on microcirculation and hypoxia following in CM-AKI. WORT (wortmannin) significantly decreased renal medullary blood flow (a), but not cortical blood flow (b) in LIPC + CM. Representative photomicrographs of kidney sections of CI-AKI with Hypoxyprobe staining (c). WORT significantly increased score of Hypoxyprobe staining in 15 and 30 min in CM + LIPC (d). Original magnification × 200. *P < 0.05, **P < 0.01, #P < 0.01; n = 6 each. The values shown are the mean ± SD

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European Journal of Medical Research

ISSN: 2047-783X

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