Clinical significance of miR-19b-3p in patients with sepsis and its regulatory role in the LPS-induced inflammatory response

Table 1 Comparison of the baseline data between the two groups of study objects

Parameters	Health (n = 98)		Sepsis (n = 103)		P value
Parameters	Mean (IQR)	K–S test (P value)	Mean (IQR) or ± SD	K–S test (P value)	P value
Age (years)	55 (43)	< 0.001	50 (44)	0.002	0.229
Gender (male/female)	58/40	–	55/48	–	0.409
BMI (kg/m²)	23.51 (21.75)	0.030	23.40 (21.88)	0.005	0.315
Scr (mg/dL)	1.03 (0.85)	0.037	1.63 (1.40)	< 0.001	< 0.001
Albumin (g/L)	35.15 (32.63)	0.026	24.25 (22.02)	0.007	< 0.001
WBC (×10⁹/L)	8.29 (6.83)	0.002	17.80 ± 5.95	0.079	< 0.001
CRP (mg/L)	6.94 (4.48)	0.025	107.98 ± 30.05	0.065	< 0.001
PCT (ng/mL)	0.06 (0.03)	< 0.001	8.89 (8.15)	0.011	< 0.001
APACHE II score	–		13.50 (11.00)	0.002	–
SOFA score	–		5.74 ± 1.41	0.200

Mean ± SD was used to express the normal distribution data, and median and interquartile range (IQR) were used to express the non-normal distribution data
BMI body mass index, Scr serum creatinine, WBC white blood cell, CRP C-reactive protein, PCT procalcitonin, APACHE acute physiology and chronic health evaluation, SOFA sequential organ failure assessment

ISSN: 2047-783X