Table 8 Mean log10-reduction (± standard deviations) of virus titer under CO2-shielding gas via hard cavitation at a frequency of 27 kHz (n = 5)
From: Novel method for reduction of virus load in blood plasma by sonication
Time | 60 min | 120 min | 180 min | 240 min | 300 min |
|---|---|---|---|---|---|
Mean log-reduction of virus titer in PBS (log10TCID50/ml) | |||||
BVDV | 1.7 (± 0.1) | 3.8 (± 0.2) | ≥ 3.8 (± 0.2) | ≥ 3.8 (± 0.2) | ≥ 3.8 (± 0.2) |
SFV | 0.7 (± 0.1) | 2.7 (± 0.1) | 4.2 (± 0.3) | 5.0 (± 0.3) | ≥ 5.7 (± 0.3) |
PRV | 1.0 (± 0.1) | 3.0 (± 0.2) | 4.7 (± 0.3) | 4.5 (± 0.3) | ≥ 5.5 (± 0.4) |
PPV | 0 (± 0) | 0 (± 0) | 0 (± 0) | 0 (± 0) | 0 (± 0) |
Mean log-reduction of virus titer in plasma (log10TCID50/ml) | |||||
BVDV | 0.5 (± 0.1) | 1.6 (± 0.1) | 1.3 (± 0.1) | 2.4 (± 0.2) | 2.5 (± 0.2) |
SFV | 0 (± 0) | 0 (± 0.1) | 1.1 (± 0.1) | 2.9 (± 0.2) | 4.6 (± 0.3) |
PRV | 0.6 (± 0.1) | 1.6 (± 0.1) | 1.9 (± 0.1) | 2.8 (± 0.2) | 3.4 (± 0.3) |
PPV | 0 (± 0) | 0 (± 0) | 0 (± 0) | 0 (± 0) | 0 (± 0) |