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Table 8 Mean log10-reduction (± standard deviations) of virus titer under CO2-shielding gas via hard cavitation at a frequency of 27 kHz (n = 5)

From: Novel method for reduction of virus load in blood plasma by sonication

Time60 min120 min180 min240 min300 min
Mean log-reduction of virus titer in PBS (log10TCID50/ml)
 BVDV1.7 (± 0.1)3.8 (± 0.2)≥ 3.8 (± 0.2)≥ 3.8 (± 0.2)≥ 3.8 (± 0.2)
 SFV0.7 (± 0.1)2.7 (± 0.1)4.2 (± 0.3)5.0 (± 0.3)≥ 5.7 (± 0.3)
 PRV1.0 (± 0.1)3.0 (± 0.2)4.7 (± 0.3)4.5 (± 0.3)≥ 5.5 (± 0.4)
 PPV0 (± 0)0 (± 0)0 (± 0)0 (± 0)0 (± 0)
Mean log-reduction of virus titer in plasma (log10TCID50/ml)
 BVDV0.5 (± 0.1)1.6 (± 0.1)1.3 (± 0.1)2.4 (± 0.2)2.5 (± 0.2)
 SFV0 (± 0)0 (± 0.1)1.1 (± 0.1)2.9 (± 0.2)4.6 (± 0.3)
 PRV0.6 (± 0.1)1.6 (± 0.1)1.9 (± 0.1)2.8 (± 0.2)3.4 (± 0.3)
 PPV0 (± 0)0 (± 0)0 (± 0)0 (± 0)0 (± 0)