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Table 1 Phenotypic resistance by MGIT 960 system to anti-TB drugs among 93 multidrug-resistant M. tuberculosis isolates and number of susceptible and resistant isolates with mutations in target genes for each drug

From: Correction to: Molecular characterization of multidrug-resistant Mycobacterium tuberculosis (MDR-TB) isolates identifies local transmission of infection in Kuwait, a country with a low incidence of TB and MDR-TB

Anti-tuberculosis drug

No. of isolates tested

No. of susceptible isolates

No. of susceptible isolates with mutationa

No. of resistant isolates

No. (%) of resistant isolates with mutationa

Rifampicin

93

0

0

93

93 (100)

Isoniazid

93

0

0

93

92 (98.9)

Pyrazinamide

46

10

0

36

30 (83.3)

Ethambutol

93

52

39b

41

38 (92.7)

Streptomycin

93

34

0

59

51 (86.4)

  1. aResistance conferring mutations were detected in rpoB for rifampicin, katG + inhA for isoniazid, pncA for pyrazinamide, embB for ethambutol, and rpsL + rrs for streptomycin
  2. bM. tuberculosis isolates with embB mutations usually confer low level of resistance to ethambutol which are often missed by the MGIT 960 system [23, 28]