Dysregulation of miR-210 is involved in the development of diabetic retinopathy and serves a regulatory role in retinal vascular endothelial cell proliferation

Table 2 Comparison of the demographic and clinical data of patients in each group

Group	Age (year)	Gender (male/female)	BMI (kg/m²)	Disease course (year)	FPG (mmol/l)	TG (mmol/l)	TC (mmol/l)	HbA1c (%)	FINS (mIU/I)	HOMA-IR
HC	50.85±5.20	28/32	21.81±2.20	–	5.14 ± 0.83	1.47±0.17	4.28±0.49	4.92±0.46	5.38±0.54	1.29±0.08
NDR	50.23±3.81	23/17	21.78±1.84	4.27±0.72	6.15±0.58*	1.50±0.14	4.40±0.51	6.61±0.59*	5.41±0.65	1.57±0.10*
NPDR	50.73±3.80	28/32	22.07±2.73	9.55±1.57^#	7.42±0.31*^,#	1.52±0.28	4.50±0.75	7.31±0.28*^,#	5.46±0.79	1.61±0.28*
PDR	51.40±3.93	26/24	22.61±3.12	12.68±1.43^#,&	8.51±0.44*^,#,&	1.55±0.26	4.57±0.73	8.00±0.34*^,#,&	5.51±0.63	1.84±0.23*^,#,&

Data are expressed as the mean ± SD or number. Multiple comparisons were made using ANOVA followed by Tamhane’s T2 tests, while the gender distribution among groups were evaluated by using Chi-square test
HC healthy control, NDR DM without DR patients, NPDR non-proliferative DR, PDR proliferative DR, FPG fasting plasma glucose, TG triacylglycerol, TC total cholesterol, HbA1c glycosylated hemoglobin, FINS fasting insulin, HOMA-IR homoeostasis model assessment of insulin resistance
*P < 0.05 compared with HC group; ^#P < 0.05 compared with NDR group; ^&P < 0.05 compared with NPDR group

ISSN: 2047-783X