Fig. 3

a Michaelis–Menten plot and b Lineweaver–Burk plot of nitrocefin hydrolysis by NDM-1 in the absence of any antibiotic, in the presence of 5 nM of streptomycin, in the presence of 5 nM of ciprofloxacin and in the presence of 5 nM each of streptomycin in combination with ciprofloxacin. 5 nM of NDM-1 was taken during the experiment. The study was done at 298 K using sodium phosphate buffer (50 mM) of pH 7.4