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Table 2 Network meta-analysis results of efficacy outcomes

From: Comparative efficacy of treatments for patients with knee osteoarthritis: a network meta-analysis

Pain

 HA

− 0.47 (− 1.6, 0.67)

0.46 (− 0.32, 1.25)

− 0.56 (− 1.18, 0.07)

0.88 (− 0.17, 1.86)

Stiffness

 1.4 (− 0.95, 3.65)

Corticosteroid

0.93 (− 0.35, 2.22)

− 0.09 (− 1.19, 1.02)

1.35 (− 0.16, 2.78)

 − 1.41 (-2.9, 0.03)

− 2.82 (− 5.35, − 0.22)

PRP

− 1.02 (− 1.76, − 0.28)

0.41 (− 0.64, 1.39)

 1.66 (0.39, 2.89)

0.25 (− 1.99, 2.56)

3.07 (1.62, 4.53)

Placebo

1.44 (0.3, 2.49)

 − 1.4 (-3.56, 0.84)

− 2.81 (− 5.82, 0.4)

0 (− 2.11, 2.25)

− 3.06 (− 5.36, − 0.63)

HA + PRP

Physical function

 HA

− 4.25 (− 12.88, 4.66)

8.37 (0.55, 16.49)

− 6.17 (− 12.15, − 0.02)

13.32 (2.86, 23.91)

Total

 2.62 (− 6.64, 11.74)

Corticosteroid

12.62 (1.48, 23.72)

− 1.94 (− 11.39, 7.41)

17.56 (4.07, 30.85)

 − 6.3 (− 12.98, 0.26)

− 8.92 (-19.39, 1.74)

PRP

− 14.56 (− 22.02, − 7.19)

4.94 (− 5.43, 15.2)

 4.14 (− 1.19, 9.21)

1.51 (-7.66, 10.7)

10.43 (4.21, 16.58)

Placebo

19.5 (8.4, 30.51)

 − 11.15 (− 19.83, − 2.62)

− 13.78 (− 26.09, − 1.39)

− 4.85 (− 13.35, 3.65)

− 15.3 (− 24.42, − 6.06)

HA + PRP

  1. HA hyaluronic acid, PRP platelet-rich plasma