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Table 1 IPRP-HPLC DAD methods for meropenem and imipenem determination

From: The stability of carbapenems before and after admixture to PMMA-cement used for replacement surgery caused by Gram-negative bacteria

Parameter

Meropenem method

Imipenem method

Flow rate [mL/min]

1.5

1

Mobile phase

75% of A and 25% of B

100% of B

Injection volume [µL]

1

Detection wavelength

300 nm

Autosampler temperature [°C]

5

Column temperature [°C]

45

Runtime [min]

4